E-ISSN 2534-9821
 
2023, Vol: 7, Issue: 6
7 / 6Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Copyright Transfer Form

Original Research

Online Publishing Date:
07 / 11 / 2021

 


Effects of l-glutamine supplementation on reducing c-reactive protein (CRP) levels and length of stay in intensive care unit post laparotomy

Daniel, Pontisomaya Parami.


Abstract
Backgrounds: Post-laparotomy ICU patients have an average length of stay in the ICU with an average of 7-14 days depending on the procedure and postoperative complications. When the body is sick or injured, glutamine will become "conditionally-essential" which is a condition where a person needs additional food or supplements. Glutamine (Gln) has been shown to have an important function for various organ systems, including the intestines, the immune system, and to maintain acid-base balance. C-reactive protein (CRP) is a sensitive inflammatory marker to assess non-specific inflammatory response and there is an inverse relationship between Gln and CRP levels (r = -0.44, p < 0.05).
Aims: L-Glutamin 20 gram intravenous per day for 3 days can reduce CRP levels and length of stay in ICU of the post-laparotomy patients.
Method: This study used a double-blind randomized clinical trial to compare a group with L-Gln supplementation and without L-Gln supplementation, for laparotomy patients who were treated in the ICU from March to June 2021.
Results: There were 40 patients divided into 2 groups. The statistical analysis results found the difference in CRP levels, p-value <0.001 and length of stay in ICU, p-value 0.011. Length of stay in the ICU of patients with high CRP was positively related with a significant correlation, r = 0.372 p = 0.018
Conclusion: L-Glutamin 20 gram intravenous per day for 3 days can reduce CRP levels and length of stay at ICU for post laparotomy patients.

Key words: C-reactive protein, Glutamine, Intensive care unit, length of stay, laparotomy


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Daniel
Articles by Pontisomaya Parami
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Daniel, Parami P. Effects of l-glutamine supplementation on reducing c-reactive protein (CRP) levels and length of stay in intensive care unit post laparotomy. Int J Med Rev Case Rep. 2021; 5(13): 20-23. doi:10.5455/IJMRCR.l-glutamin-crp-levels-postlaparotomy

Web Style

Daniel, Parami P. Effects of l-glutamine supplementation on reducing c-reactive protein (CRP) levels and length of stay in intensive care unit post laparotomy. https://www.mdpub.net/?mno=101231 [Access: April 04, 2024]. doi:10.5455/IJMRCR.l-glutamin-crp-levels-postlaparotomy

AMA (American Medical Association) Style

Daniel, Parami P. Effects of l-glutamine supplementation on reducing c-reactive protein (CRP) levels and length of stay in intensive care unit post laparotomy. Int J Med Rev Case Rep. 2021; 5(13): 20-23. doi:10.5455/IJMRCR.l-glutamin-crp-levels-postlaparotomy


Vancouver/ICMJE Style

Daniel, Parami P. Effects of l-glutamine supplementation on reducing c-reactive protein (CRP) levels and length of stay in intensive care unit post laparotomy. Int J Med Rev Case Rep. (2021), [cited April 04, 2024]; 5(13): 20-23. doi:10.5455/IJMRCR.l-glutamin-crp-levels-postlaparotomy


Harvard Style

Daniel & Parami, . P. (2021) Effects of l-glutamine supplementation on reducing c-reactive protein (CRP) levels and length of stay in intensive care unit post laparotomy. Int J Med Rev Case Rep, 5 (13), 20-23. doi:10.5455/IJMRCR.l-glutamin-crp-levels-postlaparotomy


Turabian Style

Daniel, and Pontisomaya Parami. 2021. Effects of l-glutamine supplementation on reducing c-reactive protein (CRP) levels and length of stay in intensive care unit post laparotomy. International Journal of Medical Reviews and Case Reports, 5 (13), 20-23. doi:10.5455/IJMRCR.l-glutamin-crp-levels-postlaparotomy


Chicago Style

Daniel, and Pontisomaya Parami. "Effects of l-glutamine supplementation on reducing c-reactive protein (CRP) levels and length of stay in intensive care unit post laparotomy." International Journal of Medical Reviews and Case Reports 5 (2021), 20-23. doi:10.5455/IJMRCR.l-glutamin-crp-levels-postlaparotomy


MLA (The Modern Language Association) Style

Daniel, and Pontisomaya Parami. "Effects of l-glutamine supplementation on reducing c-reactive protein (CRP) levels and length of stay in intensive care unit post laparotomy." International Journal of Medical Reviews and Case Reports 5.13 (2021), 20-23. Print. doi:10.5455/IJMRCR.l-glutamin-crp-levels-postlaparotomy


APA (American Psychological Association) Style

Daniel & Parami, . P. (2021) Effects of l-glutamine supplementation on reducing c-reactive protein (CRP) levels and length of stay in intensive care unit post laparotomy. International Journal of Medical Reviews and Case Reports, 5 (13), 20-23. doi:10.5455/IJMRCR.l-glutamin-crp-levels-postlaparotomy


Author LoginReviewer LoginAbout PublisherEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessAuthor's Rights and ObligationsPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyCorrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesDigital Archiving & Preservation PoliciesStatement of Informed ConsentAdvertising PolicyTerms of UseLicense InformationCopyright Information

About International Journal of Medical Reviews and Case Reports

International Journal of Medical Reviews and Case Reports  (Int J Med Rev Case Rep)ISSN: 2534-9821The International Journal of Medical Reviews and Ca ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information


Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the International Journal of Medical Reviews and Case Reports editorial office as follows:

Bulgarian Association of Young Surgeons (BAYS);

National Center of Public Health and Analyses (NCPHA), floor 2, office № 31,  Sofia 1431, Bulgaria.

inkov@journalmedica.com

Financial department is managed by International Sci Ink Press. 

It is a company registered in Bulgaria with registered no. 205414288 and registered address at 57 Antim I str., Vazrazhdane, Sofia, 1303, Bulgaria.

Tel: +359883427500