E-ISSN 2534-9821
 

Review Article 


Neurofilament Light Chain Measurement with Electrochemiluminescence Method (NFL-ECL) in Cerebrospinal Fluid as Promising Diagnostic Method of Amyotrophic Lateral Sclerosis: A Literature Review

Leonardo Wiranata Soesilopranoto, Yesyurun Sekundus Torrys, Randy Martianus, Tjokorda Istri Pramitasuri, Ida Ayu Sri Wijayanti, I Putu Eka Widyadharma.

Abstract
ALS is one of the neurodegenerative diseases that have high morbidity and mortality. Beside difficulties to manage, it also has a limited diagnostic method to detect ALS in early onset. Neurofilament Light Chain (NFL) is a component of cerebrospinal fluid (CSF) which regulate axon diameter calibration and conduction speed in action potential of neurons. In this review, several literatures were evaluated and selected. The NFL measurement with ECL method has high sensitivity and specificity, that makes this method reliable to use in the diagnosis of ALS.

Key words: Neurofilament Light Chain, Electrochemiluminescence, Amyotrophic lateral sclerosis, Diagnostic


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Leonardo Wiranata Soesilopranoto
Articles by Yesyurun Sekundus Torrys
Articles by Randy Martianus
Articles by Tjokorda Istri Pramitasuri
Articles by Ida Ayu Sri Wijayanti
Articles by I Putu Eka Widyadharma
on Google
on Google Scholar
Article Statistics
 Viewed: 426
Downloaded: 263
Cited: 0

How to Cite this Article
Pubmed Style

Leonardo Wiranata Soesilopranoto, Yesyurun Sekundus Torrys, Randy Martianus, Tjokorda Istri Pramitasuri, Ida Ayu Sri Wijayanti, I Putu Eka Widyadharma. Neurofilament Light Chain Measurement with Electrochemiluminescence Method (NFL-ECL) in Cerebrospinal Fluid as Promising Diagnostic Method of Amyotrophic Lateral Sclerosis: A Literature Review. Int J Med Rev Case Rep. 2018; 2(3): 53-57. doi:10.5455/IJMRCR.nfl-ecl-amyotrophic-lateral-sclerosis


Web Style

Leonardo Wiranata Soesilopranoto, Yesyurun Sekundus Torrys, Randy Martianus, Tjokorda Istri Pramitasuri, Ida Ayu Sri Wijayanti, I Putu Eka Widyadharma. Neurofilament Light Chain Measurement with Electrochemiluminescence Method (NFL-ECL) in Cerebrospinal Fluid as Promising Diagnostic Method of Amyotrophic Lateral Sclerosis: A Literature Review. http://mdpub.net/?mno=300480 [Access: December 19, 2018]. doi:10.5455/IJMRCR.nfl-ecl-amyotrophic-lateral-sclerosis


AMA (American Medical Association) Style

Leonardo Wiranata Soesilopranoto, Yesyurun Sekundus Torrys, Randy Martianus, Tjokorda Istri Pramitasuri, Ida Ayu Sri Wijayanti, I Putu Eka Widyadharma. Neurofilament Light Chain Measurement with Electrochemiluminescence Method (NFL-ECL) in Cerebrospinal Fluid as Promising Diagnostic Method of Amyotrophic Lateral Sclerosis: A Literature Review. Int J Med Rev Case Rep. 2018; 2(3): 53-57. doi:10.5455/IJMRCR.nfl-ecl-amyotrophic-lateral-sclerosis



Vancouver/ICMJE Style

Leonardo Wiranata Soesilopranoto, Yesyurun Sekundus Torrys, Randy Martianus, Tjokorda Istri Pramitasuri, Ida Ayu Sri Wijayanti, I Putu Eka Widyadharma. Neurofilament Light Chain Measurement with Electrochemiluminescence Method (NFL-ECL) in Cerebrospinal Fluid as Promising Diagnostic Method of Amyotrophic Lateral Sclerosis: A Literature Review. Int J Med Rev Case Rep. (2018), [cited December 19, 2018]; 2(3): 53-57. doi:10.5455/IJMRCR.nfl-ecl-amyotrophic-lateral-sclerosis



Harvard Style

Leonardo Wiranata Soesilopranoto, Yesyurun Sekundus Torrys, Randy Martianus, Tjokorda Istri Pramitasuri, Ida Ayu Sri Wijayanti, I Putu Eka Widyadharma (2018) Neurofilament Light Chain Measurement with Electrochemiluminescence Method (NFL-ECL) in Cerebrospinal Fluid as Promising Diagnostic Method of Amyotrophic Lateral Sclerosis: A Literature Review. Int J Med Rev Case Rep, 2 (3), 53-57. doi:10.5455/IJMRCR.nfl-ecl-amyotrophic-lateral-sclerosis



Turabian Style

Leonardo Wiranata Soesilopranoto, Yesyurun Sekundus Torrys, Randy Martianus, Tjokorda Istri Pramitasuri, Ida Ayu Sri Wijayanti, I Putu Eka Widyadharma. 2018. Neurofilament Light Chain Measurement with Electrochemiluminescence Method (NFL-ECL) in Cerebrospinal Fluid as Promising Diagnostic Method of Amyotrophic Lateral Sclerosis: A Literature Review. International Journal of Medical Reviews and Case Reports, 2 (3), 53-57. doi:10.5455/IJMRCR.nfl-ecl-amyotrophic-lateral-sclerosis



Chicago Style

Leonardo Wiranata Soesilopranoto, Yesyurun Sekundus Torrys, Randy Martianus, Tjokorda Istri Pramitasuri, Ida Ayu Sri Wijayanti, I Putu Eka Widyadharma. "Neurofilament Light Chain Measurement with Electrochemiluminescence Method (NFL-ECL) in Cerebrospinal Fluid as Promising Diagnostic Method of Amyotrophic Lateral Sclerosis: A Literature Review." International Journal of Medical Reviews and Case Reports 2 (2018), 53-57. doi:10.5455/IJMRCR.nfl-ecl-amyotrophic-lateral-sclerosis



MLA (The Modern Language Association) Style

Leonardo Wiranata Soesilopranoto, Yesyurun Sekundus Torrys, Randy Martianus, Tjokorda Istri Pramitasuri, Ida Ayu Sri Wijayanti, I Putu Eka Widyadharma. "Neurofilament Light Chain Measurement with Electrochemiluminescence Method (NFL-ECL) in Cerebrospinal Fluid as Promising Diagnostic Method of Amyotrophic Lateral Sclerosis: A Literature Review." International Journal of Medical Reviews and Case Reports 2.3 (2018), 53-57. Print. doi:10.5455/IJMRCR.nfl-ecl-amyotrophic-lateral-sclerosis



APA (American Psychological Association) Style

Leonardo Wiranata Soesilopranoto, Yesyurun Sekundus Torrys, Randy Martianus, Tjokorda Istri Pramitasuri, Ida Ayu Sri Wijayanti, I Putu Eka Widyadharma (2018) Neurofilament Light Chain Measurement with Electrochemiluminescence Method (NFL-ECL) in Cerebrospinal Fluid as Promising Diagnostic Method of Amyotrophic Lateral Sclerosis: A Literature Review. International Journal of Medical Reviews and Case Reports, 2 (3), 53-57. doi:10.5455/IJMRCR.nfl-ecl-amyotrophic-lateral-sclerosis