Abstract
Background: Leprosy is a chronic infectious disease mainly affecting the skin and peripheral nerves which may lead to disability and deformity. Leprosy has been officially eliminated from India (<1 case per 10000 population) in 2005 but we are still getting new cases of Leprosy in our setting. We have undertaken the study to find out the clinical profile and magnitude of Leprosy patients attending the tertiary care level centre of Assam and to analyse any factor behind the increasing trend of incidence. Method and Material: A hospital-based retrospective clinical study was carried out on patients diagnosed and registered in the tertiary care centre of Assam from 1st September 2011 to 31st August 2016. The data was analysed according to predefined parameters. Result: A total of 100 patients were registered over a period of 5 years with a male to female ratio of 3:1. The majority of patients were in the middle age group (31-45 years). Lepromatous leprosy was the most frequent morphological type. The clinicopathological correlation was observed in 60% of patients. AFB in the tissue section was found in 2 cases. Various deformities of the hands, feet, or eyes were seen in 37 patients. Lepra reaction was observed in 24% of the patients. Follow up cases responded well to Multidrug therapy. Conclusion: It shows that in spite of statistical elimination of Leprosy from India there are still some areas having a high incidence of multibacillary disease. Reaction and Deformities are other burdens. It highlights the need for intensification of early case detection and control.

Key words: Leprosy, Deformities, Reactions, Treatment