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The Importance of Vitamin D in Seasonal Affective Disorder and other depressive disorders

Domina Petric.

Abstract
Seasonal Affective Disorder (SAD) is a form of recurrent depressive or bipolar disorder that is characterized by episodes of major depression that tend to recur during winter usually. Vitamin D is important for serotonin synthesis and low serotonin levels are thought to be associated with depression. During the winter, levels of vitamin D are lower, which might precipitate depression symptoms in individuals with SAD, but it might also be relevant for other depressive disorders, such as major depressive disorder or bipolar disorder. Patients with depression may benefit from vitamin D supplements, especially during the late autumn and winter when sunlight-induced vitamin D production is lower, and diet enriched with tryptophan. Vitamin D supplements may be beneficial in depressed patients with high inflammatory biomarkers because studies have shown that inflammation can produce depression in vulnerable individuals by lowering plasma tryptophan and diminishing brain serotonin activity. Vitamin D supplements may also improve the efficacy of SSRIs in these patients.

Key words: depression, vitamin D, serotonin, winter


 
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Pubmed Style

Domina Petric. The Importance of Vitamin D in Seasonal Affective Disorder and other depressive disorders. Int J Med Rev Case Rep. 2021; 5(13): 48-50. doi:10.5455/IJMRCR.TheImportanceofVitaminDinSeasonalAffectiveDisorderandotherdepressivedisorders


Web Style

Domina Petric. The Importance of Vitamin D in Seasonal Affective Disorder and other depressive disorders. http://www.mdpub.net/?mno=28784 [Access: December 31, 2021]. doi:10.5455/IJMRCR.TheImportanceofVitaminDinSeasonalAffectiveDisorderandotherdepressivedisorders


AMA (American Medical Association) Style

Domina Petric. The Importance of Vitamin D in Seasonal Affective Disorder and other depressive disorders. Int J Med Rev Case Rep. 2021; 5(13): 48-50. doi:10.5455/IJMRCR.TheImportanceofVitaminDinSeasonalAffectiveDisorderandotherdepressivedisorders



Vancouver/ICMJE Style

Domina Petric. The Importance of Vitamin D in Seasonal Affective Disorder and other depressive disorders. Int J Med Rev Case Rep. (2021), [cited December 31, 2021]; 5(13): 48-50. doi:10.5455/IJMRCR.TheImportanceofVitaminDinSeasonalAffectiveDisorderandotherdepressivedisorders



Harvard Style

Domina Petric (2021) The Importance of Vitamin D in Seasonal Affective Disorder and other depressive disorders. Int J Med Rev Case Rep, 5 (13), 48-50. doi:10.5455/IJMRCR.TheImportanceofVitaminDinSeasonalAffectiveDisorderandotherdepressivedisorders



Turabian Style

Domina Petric. 2021. The Importance of Vitamin D in Seasonal Affective Disorder and other depressive disorders. International Journal of Medical Reviews and Case Reports, 5 (13), 48-50. doi:10.5455/IJMRCR.TheImportanceofVitaminDinSeasonalAffectiveDisorderandotherdepressivedisorders



Chicago Style

Domina Petric. "The Importance of Vitamin D in Seasonal Affective Disorder and other depressive disorders." International Journal of Medical Reviews and Case Reports 5 (2021), 48-50. doi:10.5455/IJMRCR.TheImportanceofVitaminDinSeasonalAffectiveDisorderandotherdepressivedisorders



MLA (The Modern Language Association) Style

Domina Petric. "The Importance of Vitamin D in Seasonal Affective Disorder and other depressive disorders." International Journal of Medical Reviews and Case Reports 5.13 (2021), 48-50. Print. doi:10.5455/IJMRCR.TheImportanceofVitaminDinSeasonalAffectiveDisorderandotherdepressivedisorders



APA (American Psychological Association) Style

Domina Petric (2021) The Importance of Vitamin D in Seasonal Affective Disorder and other depressive disorders. International Journal of Medical Reviews and Case Reports, 5 (13), 48-50. doi:10.5455/IJMRCR.TheImportanceofVitaminDinSeasonalAffectiveDisorderandotherdepressivedisorders