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Case Report
Online Published: 26 May 2020
 


Fibroblast growth factor: A target for covid-19 infection

Pedro Cuevas, Antonio Manquillo, Pedro Guillen, Guillermo Giménez-gallego.


Cited By: 2

Abstract
In the last few months, covid-19 has spread as a highly contagious pandemic. Currently no therapies have proven to be effective for the treatment of this severe illness that progresses with a strong inflammation in different organs and systems. Because fibroblast growth factor (FGF) is a potent inflammatory agent, we have tested, in one patient who didn’t respond to the protocol therapy, the effect of FGF inhibition with an anti-inflammatory and antiviral compound with a large history of medical use which was reported as the most effective anti-FGF inhibitor: dobesilate. After five days of oral treatment, dobesilate resulted in amelioration of chest radiographies as well as in clinical improvement, opening a new possible therapeutic mean to be tested in patients.

Key words: Covid-19 infection, fibroblast growth factor, dobesilate


 
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This Article Cited By the following articles

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How to Cite this Article
Pubmed Style

Cuevas P, Manquillo A, Guillen P, Giménez-gallego G. Fibroblast growth factor: A target for covid-19 infection. Int J Med Rev Case Rep. 2020; 4(5): 122-125. doi:10.5455/IJMRCR.Fibroblast-growth-factor-COVID-19

Web Style

Cuevas P, Manquillo A, Guillen P, Giménez-gallego G. Fibroblast growth factor: A target for covid-19 infection. https://www.mdpub.net/?mno=103656 [Access: April 02, 2025]. doi:10.5455/IJMRCR.Fibroblast-growth-factor-COVID-19

AMA (American Medical Association) Style

Cuevas P, Manquillo A, Guillen P, Giménez-gallego G. Fibroblast growth factor: A target for covid-19 infection. Int J Med Rev Case Rep. 2020; 4(5): 122-125. doi:10.5455/IJMRCR.Fibroblast-growth-factor-COVID-19


Vancouver/ICMJE Style

Cuevas P, Manquillo A, Guillen P, Giménez-gallego G. Fibroblast growth factor: A target for covid-19 infection. Int J Med Rev Case Rep. (2020), [cited April 02, 2025]; 4(5): 122-125. doi:10.5455/IJMRCR.Fibroblast-growth-factor-COVID-19


Harvard Style

Cuevas, P., Manquillo, . A., Guillen, . P. & Giménez-gallego, . G. (2020) Fibroblast growth factor: A target for covid-19 infection. Int J Med Rev Case Rep, 4 (5), 122-125. doi:10.5455/IJMRCR.Fibroblast-growth-factor-COVID-19


Turabian Style

Cuevas, Pedro, Antonio Manquillo, Pedro Guillen, and Guillermo Giménez-gallego. 2020. Fibroblast growth factor: A target for covid-19 infection. International Journal of Medical Reviews and Case Reports, 4 (5), 122-125. doi:10.5455/IJMRCR.Fibroblast-growth-factor-COVID-19


Chicago Style

Cuevas, Pedro, Antonio Manquillo, Pedro Guillen, and Guillermo Giménez-gallego. "Fibroblast growth factor: A target for covid-19 infection." International Journal of Medical Reviews and Case Reports 4 (2020), 122-125. doi:10.5455/IJMRCR.Fibroblast-growth-factor-COVID-19


MLA (The Modern Language Association) Style

Cuevas, Pedro, Antonio Manquillo, Pedro Guillen, and Guillermo Giménez-gallego. "Fibroblast growth factor: A target for covid-19 infection." International Journal of Medical Reviews and Case Reports 4.5 (2020), 122-125. Print. doi:10.5455/IJMRCR.Fibroblast-growth-factor-COVID-19


APA (American Psychological Association) Style

Cuevas, P., Manquillo, . A., Guillen, . P. & Giménez-gallego, . G. (2020) Fibroblast growth factor: A target for covid-19 infection. International Journal of Medical Reviews and Case Reports, 4 (5), 122-125. doi:10.5455/IJMRCR.Fibroblast-growth-factor-COVID-19


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