E-ISSN 2534-9821
 

Original Research 


Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy

Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari.

Abstract
Leprosy is chronic infectious disease caused by the intracellular parasitic pathogen Mycobacterium Leprae involves accumulation of highly reactive oxygen species (ROS) production and decreased levels of antioxidant in affected individuals. The present treatment method available for leprosy is MDT (Multi Drug Therapy) from WHO (World Health Organization) involves combination of Rifampicin, Dapsone and Clofazimine. In this cohort prospective study, we have investigated total antioxidant capacity (TAC) in 16 multibacillary leprosy patients before and after 3 months of MDT-MB WHO. In this study, we present that mean values of total antioxidant capacity (TAC) after 3 months of MDT-MB WHO were higher than before treated. From the sample groups in this study, we also found an decrease TAC levels in higher bacterial index after 3 months of MDT-MB WHO, this further increases significantly (p<0.05). Hence we conclude that 3 months giving of MDT-MB WHO increase the total antioxidant capacity.

Key words: Total antioxidant capacity (TAC), MDT-MB WHO, Leprosy MB


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Dinie Ramdhani Kusuma
Articles by Safruddin Amin
Articles by Khairuddin Djawad
Articles by Srivitayani Muchtar
Articles by Sitti Nur Rahmah
Articles by Idham Jaya Ganda
Articles by Agussalim Bukhari
on Google
on Google Scholar
Article Statistics
 Viewed: 1518
Downloaded: 365
Cited: 0


How to Cite this Article
Pubmed Style

Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari. Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. Int J Med Rev Case Rep. 2018; 2(4): 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy


Web Style

Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari. Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. http://mdpub.net/?mno=297595 [Access: September 20, 2019]. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy


AMA (American Medical Association) Style

Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari. Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. Int J Med Rev Case Rep. 2018; 2(4): 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy



Vancouver/ICMJE Style

Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari. Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. Int J Med Rev Case Rep. (2018), [cited September 20, 2019]; 2(4): 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy



Harvard Style

Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari (2018) Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. Int J Med Rev Case Rep, 2 (4), 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy



Turabian Style

Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari. 2018. Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. International Journal of Medical Reviews and Case Reports, 2 (4), 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy



Chicago Style

Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari. "Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy." International Journal of Medical Reviews and Case Reports 2 (2018), 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy



MLA (The Modern Language Association) Style

Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari. "Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy." International Journal of Medical Reviews and Case Reports 2.4 (2018), 136-142. Print. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy



APA (American Psychological Association) Style

Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari (2018) Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. International Journal of Medical Reviews and Case Reports, 2 (4), 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy