E-ISSN 2534-9821
 

Original Research (Original Article) 


Effect of obesity on the relationship between nonalcoholic fatty liver disease and glomerular filtration rate

Khadijah Khairunnisa Hasyim, St Rabiul Zatalia, Haerani Rasyid, Hasyim Kasim, Syakib Bakri, A M Luthfi Parewangi, Andi Makbul Aman, Himawan Dharmayani Sanusi, Arifin Seweng.

Abstract
Background: Obesity is an important risk factor for the incidence of NAFLD and also associated with the incidence of CKD). In obesity, especially at the beginning, are associated with the increase of GFR, in which GFR may increase 150-200% depending on the degree of obesity. This study was conducted to determine the effect of obesity on the relationship between NAFLD and GFR.
Method: This was an analytical study with a cross-sectional design. Subjects were men and women aged from 18-80 years with abdominal ultrasound indicated fatty liver in Wahidin Sudirohusodo hospital, Makassar, Indonesia.
Result: The proportion of subjects with GFR <90 ml/min/1.73 m2 was found to be significantly higher in the NAFLD than in non NAFLD (59,6% vs 45,9%, p< 0.05) and subjects with stage 3-4 CKD (GFR <60 ml/min/1.73 m2) was found to be significantly higher in the NAFLD (34,0% vs 14,9%, p< 0.05). The proportion of subjects with GFR <90 ml/min/1.73 m2 was found to be significantly higher in non-obese than in obese (68,4% vs 51,0%, p< 0.05). In the NAFLD, it was found that the proportion of subjects with GFR <90 ml/min/1.73 m2 was significantly higher in non-obese than in obese (74,1% vs 54,45, p< 0.05). In the non NAFLD, the proportion of subjects with GFR < 90 was also higher in non-obese than in obese (56,0% vs 40,8%, p< 0.05).
Conclusion: Obese with NAFLD have higher GFR compared to non-obese subjects with NAFLD.

Key words: Obesity, nonalcoholic fatty liver disease, glomerular filtration rate


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Khadijah Khairunnisa Hasyim
Articles by St Rabiul Zatalia
Articles by Haerani Rasyid
Articles by Hasyim Kasim
Articles by Syakib Bakri
Articles by A M Luthfi Parewangi
Articles by Andi Makbul Aman
Articles by Himawan Dharmayani Sanusi
Articles by Arifin Seweng
on Google
on Google Scholar
Article Statistics
 Viewed: 823
Downloaded: 60
Cited: 0


How to Cite this Article
Pubmed Style

Hasyim KK, Zatalia SR, Rasyid H, Kasim H, Bakri S, Parewangi AML, Aman AM, Sanusi HD, Seweng A. Effect of obesity on the relationship between nonalcoholic fatty liver disease and glomerular filtration rate. Int J Med Rev Case Rep. 2019; 3(6): 317-321. doi:10.5455/IJMRCR.non-alcoholic-fatty-liver-gfr


Web Style

Hasyim KK, Zatalia SR, Rasyid H, Kasim H, Bakri S, Parewangi AML, Aman AM, Sanusi HD, Seweng A. Effect of obesity on the relationship between nonalcoholic fatty liver disease and glomerular filtration rate. http://mdpub.net/?mno=31822 [Access: September 20, 2019]. doi:10.5455/IJMRCR.non-alcoholic-fatty-liver-gfr


AMA (American Medical Association) Style

Hasyim KK, Zatalia SR, Rasyid H, Kasim H, Bakri S, Parewangi AML, Aman AM, Sanusi HD, Seweng A. Effect of obesity on the relationship between nonalcoholic fatty liver disease and glomerular filtration rate. Int J Med Rev Case Rep. 2019; 3(6): 317-321. doi:10.5455/IJMRCR.non-alcoholic-fatty-liver-gfr



Vancouver/ICMJE Style

Hasyim KK, Zatalia SR, Rasyid H, Kasim H, Bakri S, Parewangi AML, Aman AM, Sanusi HD, Seweng A. Effect of obesity on the relationship between nonalcoholic fatty liver disease and glomerular filtration rate. Int J Med Rev Case Rep. (2019), [cited September 20, 2019]; 3(6): 317-321. doi:10.5455/IJMRCR.non-alcoholic-fatty-liver-gfr



Harvard Style

Hasyim, K. K., Zatalia, . S. R., Rasyid, . H., Kasim, . H., Bakri, . S., Parewangi, . A. M. L., Aman, . A. M., Sanusi, . H. D. & Seweng, . A. (2019) Effect of obesity on the relationship between nonalcoholic fatty liver disease and glomerular filtration rate. Int J Med Rev Case Rep, 3 (6), 317-321. doi:10.5455/IJMRCR.non-alcoholic-fatty-liver-gfr



Turabian Style

Hasyim, Khadijah Khairunnisa, St Rabiul Zatalia, Haerani Rasyid, Hasyim Kasim, Syakib Bakri, A M Luthfi Parewangi, Andi Makbul Aman, Himawan Dharmayani Sanusi, and Arifin Seweng. 2019. Effect of obesity on the relationship between nonalcoholic fatty liver disease and glomerular filtration rate. International Journal of Medical Reviews and Case Reports, 3 (6), 317-321. doi:10.5455/IJMRCR.non-alcoholic-fatty-liver-gfr



Chicago Style

Hasyim, Khadijah Khairunnisa, St Rabiul Zatalia, Haerani Rasyid, Hasyim Kasim, Syakib Bakri, A M Luthfi Parewangi, Andi Makbul Aman, Himawan Dharmayani Sanusi, and Arifin Seweng. "Effect of obesity on the relationship between nonalcoholic fatty liver disease and glomerular filtration rate." International Journal of Medical Reviews and Case Reports 3 (2019), 317-321. doi:10.5455/IJMRCR.non-alcoholic-fatty-liver-gfr



MLA (The Modern Language Association) Style

Hasyim, Khadijah Khairunnisa, St Rabiul Zatalia, Haerani Rasyid, Hasyim Kasim, Syakib Bakri, A M Luthfi Parewangi, Andi Makbul Aman, Himawan Dharmayani Sanusi, and Arifin Seweng. "Effect of obesity on the relationship between nonalcoholic fatty liver disease and glomerular filtration rate." International Journal of Medical Reviews and Case Reports 3.6 (2019), 317-321. Print. doi:10.5455/IJMRCR.non-alcoholic-fatty-liver-gfr



APA (American Psychological Association) Style

Hasyim, K. K., Zatalia, . S. R., Rasyid, . H., Kasim, . H., Bakri, . S., Parewangi, . A. M. L., Aman, . A. M., Sanusi, . H. D. & Seweng, . A. (2019) Effect of obesity on the relationship between nonalcoholic fatty liver disease and glomerular filtration rate. International Journal of Medical Reviews and Case Reports, 3 (6), 317-321. doi:10.5455/IJMRCR.non-alcoholic-fatty-liver-gfr