E-ISSN 2534-9821
 

Case Report 


Cholestatic hepatitis as a presentation of Epstein-Barr virus infection

Mayara Nogueira, Joana Gaspar, Susana Gomes.

Abstract
Epstein-Barr virus (EBV) infection in children and adolescents clinically presents as infectious mononucleosis and usually leads to self limited elevation of liver enzymes but cholestatic hepatitis with jaundice is rare. We present a 16-year-old female with fever, fatigue, vomiting, choluria and jaundice. Physical examination showed a painful abdomen and the remaining examination was unremarkable. Laboratory tests results revealed leucocytosis and activated lymphocytes, normal haemoglobin level, the elevation of transaminases more than 7 times the upper limit, cholestasis and hypoalbuminemia. The abdominal ultrasound showed mild hepatosplenomegaly. Viral serologies revealed positive EBV viral capsid antibody IgM and negative IgG and were negative for other viral agents. Later she developed haemolytic anaemia. She received support treatment and fully recovered. We emphasize that EBV infection should be considered in patients with cholestatic hepatitis with jaundice.

Key words: Epstein-Barr virus, cholestasis, hepatitis, hyperbilirubinemia, jaundice


 
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How to Cite this Article
Pubmed Style

Nogueira M, Gaspar J, Gomes S. Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. Int J Med Rev Case Rep. 2021; 5(5): 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058


Web Style

Nogueira M, Gaspar J, Gomes S. Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. http://www.mdpub.net/?mno=53293 [Access: December 31, 2021]. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058


AMA (American Medical Association) Style

Nogueira M, Gaspar J, Gomes S. Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. Int J Med Rev Case Rep. 2021; 5(5): 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



Vancouver/ICMJE Style

Nogueira M, Gaspar J, Gomes S. Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. Int J Med Rev Case Rep. (2021), [cited December 31, 2021]; 5(5): 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



Harvard Style

Nogueira, M., Gaspar, . J. & Gomes, . S. (2021) Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. Int J Med Rev Case Rep, 5 (5), 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



Turabian Style

Nogueira, Mayara, Joana Gaspar, and Susana Gomes. 2021. Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. International Journal of Medical Reviews and Case Reports, 5 (5), 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



Chicago Style

Nogueira, Mayara, Joana Gaspar, and Susana Gomes. "Cholestatic hepatitis as a presentation of Epstein-Barr virus infection." International Journal of Medical Reviews and Case Reports 5 (2021), 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



MLA (The Modern Language Association) Style

Nogueira, Mayara, Joana Gaspar, and Susana Gomes. "Cholestatic hepatitis as a presentation of Epstein-Barr virus infection." International Journal of Medical Reviews and Case Reports 5.5 (2021), 39-41. Print. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058



APA (American Psychological Association) Style

Nogueira, M., Gaspar, . J. & Gomes, . S. (2021) Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. International Journal of Medical Reviews and Case Reports, 5 (5), 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058