E-ISSN 2534-9821
 

Case Series 


Rectal gastrointestinal stromal tumor: Retrospective analyses of clinicopatholoical factors and survival outcomes

Ihtisham Ul Haq, Osama Shakeel, Abdul Wahid Anwer, Aun Jamal Gill, Irfan Bashir, Awais Amjad Malik, Muhammad Fahd Shah, Hannan Ali, Shahid Khattak, Aamir Ali Syed.

Abstract
INTRODUCTION: The term Gastrointestinal Stromal Tumor (GIST) was coined in 1983. Rectal GIST is a rare disease. Imatinib with curative resection is the cornerstone for the management of the disease.
METHODOLOGY: Itís a retrospective case series of two patients treated at Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&RC).
RESULTS: Two patients presented at SKMCH&RC with history of perianal pain. Diagnostic workup was performed. MRI showed rectal mass which was confirmed as rectal GIST on biopsy. CD117 was positive in both cases. Metastatic workup was negative. One patient received neoadjuvant imatinib, the other underwent upfront surgery. Both patients received adjuvant imatinib. One patient with a closed resection margin had recurrence after 5 years of treatment. She underwent surgical resection for recurrence. Both of the patients are now alive without disease.
CONCLUSION: Although this data is first to be reported from this part of the world, however, due to the small number of reported patients, this study cannot be used as a guideline for the management of disease

Key words: Gastrointestinal stromal tumors, Gastrointestinal stromal tumor of rectum, Rare cancer of rectum, GIST, Rare site of GIST


 
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How to Cite this Article
Pubmed Style

Haq IU, Shakeel O, Anwer AW, Gill AJ, Bashir I, Malik AA, Shah MF, Ali H, Khattak S, Syed AA. Rectal gastrointestinal stromal tumor: Retrospective analyses of clinicopatholoical factors and survival outcomes. Int J Med Rev Case Rep. 2020; 4(6): 17-20. doi:10.5455/IJMRCR.rectal-gist-retrospective


Web Style

Haq IU, Shakeel O, Anwer AW, Gill AJ, Bashir I, Malik AA, Shah MF, Ali H, Khattak S, Syed AA. Rectal gastrointestinal stromal tumor: Retrospective analyses of clinicopatholoical factors and survival outcomes. http://www.mdpub.net/?mno=110900 [Access: August 08, 2020]. doi:10.5455/IJMRCR.rectal-gist-retrospective


AMA (American Medical Association) Style

Haq IU, Shakeel O, Anwer AW, Gill AJ, Bashir I, Malik AA, Shah MF, Ali H, Khattak S, Syed AA. Rectal gastrointestinal stromal tumor: Retrospective analyses of clinicopatholoical factors and survival outcomes. Int J Med Rev Case Rep. 2020; 4(6): 17-20. doi:10.5455/IJMRCR.rectal-gist-retrospective



Vancouver/ICMJE Style

Haq IU, Shakeel O, Anwer AW, Gill AJ, Bashir I, Malik AA, Shah MF, Ali H, Khattak S, Syed AA. Rectal gastrointestinal stromal tumor: Retrospective analyses of clinicopatholoical factors and survival outcomes. Int J Med Rev Case Rep. (2020), [cited August 08, 2020]; 4(6): 17-20. doi:10.5455/IJMRCR.rectal-gist-retrospective



Harvard Style

Haq, I. U., Shakeel, . O., Anwer, . A. W., Gill, . A. J., Bashir, . I., Malik, . A. A., Shah, . M. F., Ali, . H., Khattak, . S. & Syed, . A. A. (2020) Rectal gastrointestinal stromal tumor: Retrospective analyses of clinicopatholoical factors and survival outcomes. Int J Med Rev Case Rep, 4 (6), 17-20. doi:10.5455/IJMRCR.rectal-gist-retrospective



Turabian Style

Haq, Ihtisham Ul, Osama Shakeel, Abdul Wahid Anwer, Aun Jamal Gill, Irfan Bashir, Awais Amjad Malik, Muhammad Fahd Shah, Hannan Ali, Shahid Khattak, and Aamir Ali Syed. 2020. Rectal gastrointestinal stromal tumor: Retrospective analyses of clinicopatholoical factors and survival outcomes. International Journal of Medical Reviews and Case Reports, 4 (6), 17-20. doi:10.5455/IJMRCR.rectal-gist-retrospective



Chicago Style

Haq, Ihtisham Ul, Osama Shakeel, Abdul Wahid Anwer, Aun Jamal Gill, Irfan Bashir, Awais Amjad Malik, Muhammad Fahd Shah, Hannan Ali, Shahid Khattak, and Aamir Ali Syed. "Rectal gastrointestinal stromal tumor: Retrospective analyses of clinicopatholoical factors and survival outcomes." International Journal of Medical Reviews and Case Reports 4 (2020), 17-20. doi:10.5455/IJMRCR.rectal-gist-retrospective



MLA (The Modern Language Association) Style

Haq, Ihtisham Ul, Osama Shakeel, Abdul Wahid Anwer, Aun Jamal Gill, Irfan Bashir, Awais Amjad Malik, Muhammad Fahd Shah, Hannan Ali, Shahid Khattak, and Aamir Ali Syed. "Rectal gastrointestinal stromal tumor: Retrospective analyses of clinicopatholoical factors and survival outcomes." International Journal of Medical Reviews and Case Reports 4.6 (2020), 17-20. Print. doi:10.5455/IJMRCR.rectal-gist-retrospective



APA (American Psychological Association) Style

Haq, I. U., Shakeel, . O., Anwer, . A. W., Gill, . A. J., Bashir, . I., Malik, . A. A., Shah, . M. F., Ali, . H., Khattak, . S. & Syed, . A. A. (2020) Rectal gastrointestinal stromal tumor: Retrospective analyses of clinicopatholoical factors and survival outcomes. International Journal of Medical Reviews and Case Reports, 4 (6), 17-20. doi:10.5455/IJMRCR.rectal-gist-retrospective