E-ISSN 2534-9821
 

Case Report
Online Published: 27 Dec 2023
 


Synchronous Primary Malignant Neoplasms of Cervix and Endometrium: A Rare Case Report

Tarini Sonwani, Gaurav Khanna.


Abstract
Background: Female genital tract synchronous primary tumors are highly uncommon. Synchronous tumors affecting both the endometrium and the cervix are uncommon. We discuss a rare instance of a 71-year-old woman with uterine endometrioid adenocarcinoma and squamous cell carcinoma (SCC) of the cervix.
Case report: A 71-years old unmarried woman presented with postmenopausal bleeding for two months. Per speculum examination showed a tiny growth at the external os. Rectovaginal examination revealed ballooned up cervix with growth ~4-5cm, bulky uterus ~8 weeks in size, normal bilateral parametria, and rectal mucosa. MRI revealed a mass in the uterus involving the cervix and lower uterine segment with enlarged bilateral internal iliac lymph nodes. Endometrial biopsy was reported as a poorly differentiated carcinoma. She underwent radical hysterectomy with bilateral salpingo-oophorectomy, bilateral pelvic lymph node dissection, para-aortic lymph node dissection, and infracolic omentectomy. Final histopathology revealed the synchronous occurrence of primary neoplasms of SCC of the cervix (stage Ib3) and endometrioid adenocarcinoma endometrium (stage Ib). She received adjuvant radiation therapy and was clinically disease-free 26 months post-surgery.
Conclusion: Synchronous malignancies of the endometrium and cervix are rare. Knowledge of synchronous primaries' occurrence is needed to plan appropriate adjuvant treatment. Adjuvant treatment is based on the stage of individual primaries. The presentation stage and extent of the disease determine the prognosis of the patients.

Key words: synchronous malignancies, squamous cell carcinoma, endometrioid adenocarcinoma, cervix


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Tarini Sonwani
Articles by Gaurav Khanna
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Sonwani T, Khanna G. Synchronous Primary Malignant Neoplasms of Cervix and Endometrium: A Rare Case Report. Int J Med Rev Case Rep. 2023; 7(8): 36-38. doi:10.5455/IJMRCR.172-1683908433


Web Style

Sonwani T, Khanna G. Synchronous Primary Malignant Neoplasms of Cervix and Endometrium: A Rare Case Report. https://www.mdpub.net/?mno=153092 [Access: September 12, 2024]. doi:10.5455/IJMRCR.172-1683908433


AMA (American Medical Association) Style

Sonwani T, Khanna G. Synchronous Primary Malignant Neoplasms of Cervix and Endometrium: A Rare Case Report. Int J Med Rev Case Rep. 2023; 7(8): 36-38. doi:10.5455/IJMRCR.172-1683908433



Vancouver/ICMJE Style

Sonwani T, Khanna G. Synchronous Primary Malignant Neoplasms of Cervix and Endometrium: A Rare Case Report. Int J Med Rev Case Rep. (2023), [cited September 12, 2024]; 7(8): 36-38. doi:10.5455/IJMRCR.172-1683908433



Harvard Style

Sonwani, T. & Khanna, . G. (2023) Synchronous Primary Malignant Neoplasms of Cervix and Endometrium: A Rare Case Report. Int J Med Rev Case Rep, 7 (8), 36-38. doi:10.5455/IJMRCR.172-1683908433



Turabian Style

Sonwani, Tarini, and Gaurav Khanna. 2023. Synchronous Primary Malignant Neoplasms of Cervix and Endometrium: A Rare Case Report. International Journal of Medical Reviews and Case Reports, 7 (8), 36-38. doi:10.5455/IJMRCR.172-1683908433



Chicago Style

Sonwani, Tarini, and Gaurav Khanna. "Synchronous Primary Malignant Neoplasms of Cervix and Endometrium: A Rare Case Report." International Journal of Medical Reviews and Case Reports 7 (2023), 36-38. doi:10.5455/IJMRCR.172-1683908433



MLA (The Modern Language Association) Style

Sonwani, Tarini, and Gaurav Khanna. "Synchronous Primary Malignant Neoplasms of Cervix and Endometrium: A Rare Case Report." International Journal of Medical Reviews and Case Reports 7.8 (2023), 36-38. Print. doi:10.5455/IJMRCR.172-1683908433



APA (American Psychological Association) Style

Sonwani, T. & Khanna, . G. (2023) Synchronous Primary Malignant Neoplasms of Cervix and Endometrium: A Rare Case Report. International Journal of Medical Reviews and Case Reports, 7 (8), 36-38. doi:10.5455/IJMRCR.172-1683908433