E-ISSN 2534-9821
 

Case Report 


Contemporaneous cystic pheochromocytoma and medullary carcinoma of thyroid- a rare clinical presentation.

Ninad Tamboli, Vivek Revankar, Ravi Jha, Sreenivas J, Keshavamurthy R.

Abstract
Introduction: Although Pheochromocytoma (PHEO) is usually a solid tumour, rarely it can present as a cystic lesion. Very few cases of MEN 2A with contemporaneous cystic pheochromocytoma and medullary carcinoma of the thyroid (MTC) are reported in the literature. Here, we present a case of young women with incidentally detected cystic pheochromocytoma with synchronous medullary carcinoma of the thyroid gland and discuss its management.
Case report: 28 years old female referred to our centre with incidentally detected left adrenal mass. Clinical history was insignificant. On examination pulse and blood pressure were normal. Neck examination showed multinodular thyroid swelling with cervical lymphadenopathy. FNAC of thyroid nodule revealed MTC. CECT was showed a cystic lesion measuring 8.7x 9.4x 9.6 cm with irregular asymmetric wall thickening with contrast enhancement. On evaluation, 24-hours urinary normetanephrine and metanephrine were significantly elevated (4355.90 µg and 4012.42 µg, respectively). The rest of the functional workup was normal. The patient underwent Left open adrenalectomy followed by total thyroidectomy with central neck lymph node dissection one month later. 24-hour urinary metanephrines at 3 months follow up were normal.
Conclusion: Although Cystic adrenal masses are often asymptomatic, they can be functional.
A young patient with pheochromocytoma should be evaluated for possible MTC.
Genetic and phenotypic correlation is important in management decisions.
Preoperative optimization and intensive intraoperative monitoring by experienced anaesthetists are vital for successful surgical outcomes.
In MEN 2 Syndrome Pheochromocytoma is often multifocal, bilateral and recurrent. Hence, long term follow up is important

Key words: Cystic Pheochromocytoma, MEN 2A, Hereditary pheochromocytoma, medullary carcinoma of thyroid


 
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How to Cite this Article
Pubmed Style

Tamboli N, Revankar V, Jha R, J S, R K. Contemporaneous cystic pheochromocytoma and medullary carcinoma of thyroid- a rare clinical presentation.. Int J Med Rev Case Rep. 2021; 5(11): 10-15. doi:10.5455/IJMRCR.cystic-pheochromocytoma-medullary-carcinoma-thyroid


Web Style

Tamboli N, Revankar V, Jha R, J S, R K. Contemporaneous cystic pheochromocytoma and medullary carcinoma of thyroid- a rare clinical presentation.. https://www.mdpub.net/?mno=115267 [Access: December 06, 2023]. doi:10.5455/IJMRCR.cystic-pheochromocytoma-medullary-carcinoma-thyroid


AMA (American Medical Association) Style

Tamboli N, Revankar V, Jha R, J S, R K. Contemporaneous cystic pheochromocytoma and medullary carcinoma of thyroid- a rare clinical presentation.. Int J Med Rev Case Rep. 2021; 5(11): 10-15. doi:10.5455/IJMRCR.cystic-pheochromocytoma-medullary-carcinoma-thyroid



Vancouver/ICMJE Style

Tamboli N, Revankar V, Jha R, J S, R K. Contemporaneous cystic pheochromocytoma and medullary carcinoma of thyroid- a rare clinical presentation.. Int J Med Rev Case Rep. (2021), [cited December 06, 2023]; 5(11): 10-15. doi:10.5455/IJMRCR.cystic-pheochromocytoma-medullary-carcinoma-thyroid



Harvard Style

Tamboli, N., Revankar, . V., Jha, . R., J, . S. & R, . K. (2021) Contemporaneous cystic pheochromocytoma and medullary carcinoma of thyroid- a rare clinical presentation.. Int J Med Rev Case Rep, 5 (11), 10-15. doi:10.5455/IJMRCR.cystic-pheochromocytoma-medullary-carcinoma-thyroid



Turabian Style

Tamboli, Ninad, Vivek Revankar, Ravi Jha, Sreenivas J, and Keshavamurthy R. 2021. Contemporaneous cystic pheochromocytoma and medullary carcinoma of thyroid- a rare clinical presentation.. International Journal of Medical Reviews and Case Reports, 5 (11), 10-15. doi:10.5455/IJMRCR.cystic-pheochromocytoma-medullary-carcinoma-thyroid



Chicago Style

Tamboli, Ninad, Vivek Revankar, Ravi Jha, Sreenivas J, and Keshavamurthy R. "Contemporaneous cystic pheochromocytoma and medullary carcinoma of thyroid- a rare clinical presentation.." International Journal of Medical Reviews and Case Reports 5 (2021), 10-15. doi:10.5455/IJMRCR.cystic-pheochromocytoma-medullary-carcinoma-thyroid



MLA (The Modern Language Association) Style

Tamboli, Ninad, Vivek Revankar, Ravi Jha, Sreenivas J, and Keshavamurthy R. "Contemporaneous cystic pheochromocytoma and medullary carcinoma of thyroid- a rare clinical presentation.." International Journal of Medical Reviews and Case Reports 5.11 (2021), 10-15. Print. doi:10.5455/IJMRCR.cystic-pheochromocytoma-medullary-carcinoma-thyroid



APA (American Psychological Association) Style

Tamboli, N., Revankar, . V., Jha, . R., J, . S. & R, . K. (2021) Contemporaneous cystic pheochromocytoma and medullary carcinoma of thyroid- a rare clinical presentation.. International Journal of Medical Reviews and Case Reports, 5 (11), 10-15. doi:10.5455/IJMRCR.cystic-pheochromocytoma-medullary-carcinoma-thyroid