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Case Report

Online Publishing Date:
29 / 07 / 2020

 


Breast reconstruction using Deep Inferior Epigastric Perforator (DIEP) flap in a patient with heterozygous Factor V Leiden: A case report

Madhumita Gupta, Ertan Erel.


Abstract
Factor V Leiden (FVLeiden) mutation is the commonest type of inherited thrombophilia. Free tissue transfer is very rarely used in such patients due to concerns about microvascular thrombosis and flap failure. Even when rarely offered, the peri-operative antithrombotic regimen for such cases is widely varied and based of personal experiences and preference. These regimens usually include multiple pharmacologic agents but their real benefit is based merely on anecdotal evidence. On the other hand, the potential complications of such drugs are well established in literature. Deep Inferior Epigastric Perforator (DIEP) flap is the most widely used autologous breast reconstruction technique. Here, we report a case of successful free DIEP flap breast reconstruction in a lady with heterozygous FVLeiden mutation. We have described our approach to this patient, including the simple single drug anticoagulation regimen used as advised by the hematologists for venous thromboembolism (VTE) prophylaxis. We have compared our approach to that of others who have reported similar cases before. Our report shows that it is feasible to offer successful free tissue breast reconstruction to these patients by following meticulous surgical technique without the need of additional systemic antithrombotic agents over and above the simple regimen indicated for general VTE prophylaxis.

Key words: DIEP flap, thrombophilia, Factor V Leiden, thromboprophylaxis


 
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How to Cite this Article
Pubmed Style

Gupta M, Erel E. Breast reconstruction using Deep Inferior Epigastric Perforator (DIEP) flap in a patient with heterozygous Factor V Leiden: A case report. Int J Med Rev Case Rep. 2020; 4(10): 86-91. doi:10.5455/IJMRCR.breast-reconstruction-diep-flap

Web Style

Gupta M, Erel E. Breast reconstruction using Deep Inferior Epigastric Perforator (DIEP) flap in a patient with heterozygous Factor V Leiden: A case report. https://www.mdpub.net/?mno=119500 [Access: April 04, 2024]. doi:10.5455/IJMRCR.breast-reconstruction-diep-flap

AMA (American Medical Association) Style

Gupta M, Erel E. Breast reconstruction using Deep Inferior Epigastric Perforator (DIEP) flap in a patient with heterozygous Factor V Leiden: A case report. Int J Med Rev Case Rep. 2020; 4(10): 86-91. doi:10.5455/IJMRCR.breast-reconstruction-diep-flap


Vancouver/ICMJE Style

Gupta M, Erel E. Breast reconstruction using Deep Inferior Epigastric Perforator (DIEP) flap in a patient with heterozygous Factor V Leiden: A case report. Int J Med Rev Case Rep. (2020), [cited April 04, 2024]; 4(10): 86-91. doi:10.5455/IJMRCR.breast-reconstruction-diep-flap


Harvard Style

Gupta, M. & Erel, . E. (2020) Breast reconstruction using Deep Inferior Epigastric Perforator (DIEP) flap in a patient with heterozygous Factor V Leiden: A case report. Int J Med Rev Case Rep, 4 (10), 86-91. doi:10.5455/IJMRCR.breast-reconstruction-diep-flap


Turabian Style

Gupta, Madhumita, and Ertan Erel. 2020. Breast reconstruction using Deep Inferior Epigastric Perforator (DIEP) flap in a patient with heterozygous Factor V Leiden: A case report. International Journal of Medical Reviews and Case Reports, 4 (10), 86-91. doi:10.5455/IJMRCR.breast-reconstruction-diep-flap


Chicago Style

Gupta, Madhumita, and Ertan Erel. "Breast reconstruction using Deep Inferior Epigastric Perforator (DIEP) flap in a patient with heterozygous Factor V Leiden: A case report." International Journal of Medical Reviews and Case Reports 4 (2020), 86-91. doi:10.5455/IJMRCR.breast-reconstruction-diep-flap


MLA (The Modern Language Association) Style

Gupta, Madhumita, and Ertan Erel. "Breast reconstruction using Deep Inferior Epigastric Perforator (DIEP) flap in a patient with heterozygous Factor V Leiden: A case report." International Journal of Medical Reviews and Case Reports 4.10 (2020), 86-91. Print. doi:10.5455/IJMRCR.breast-reconstruction-diep-flap


APA (American Psychological Association) Style

Gupta, M. & Erel, . E. (2020) Breast reconstruction using Deep Inferior Epigastric Perforator (DIEP) flap in a patient with heterozygous Factor V Leiden: A case report. International Journal of Medical Reviews and Case Reports, 4 (10), 86-91. doi:10.5455/IJMRCR.breast-reconstruction-diep-flap


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