Abstract
Objective: The major objective was to determine how percutaneous nephrolithotomy in patients with chronic renal disease affected their long-term prognosis.
Method: Prospective data collection involved 208 individuals who received percutaneous nephrolithotomy between October 2020 to October 2021. A 4-variable variation of the diet in renal disease equation was used to retroactively determine the predicted glomerular filtration rate for each patient. According to National Kidney Foundation recommendations, individuals were graded for chronic renal disease.
Result: Preoperative glomerular filtration rate was less than 50 ml per minute/1.72 m2 in a total of 140 patients (12.7%). The analysis included those who had been watched for at least six months. The average ± SD age of the 140 patients in the research was 54.2 ± 12.0 years. 15.1% of patients had perioperative and postoperative problems. The renal function had improved in 29.3% of patients at a mean follow-up of 43.3± 22.6 months, although it had remained stable or worsened in 54.1% and 16.3% of patients, respectively. Diabetic and preoperative or surgical comorbidities indicated renal function in multivariate regression analysis. At 4 months after surgery, the stone-free rate was 80.1%. 35 of these patients (25.2%) experienced stone recurrence during long-term follow-up. 10 of the 35 patients (34.1%) with residual stones showed spontaneous stone passage, however 7 (22.7%) of these patients also had larger residual stones.
Conclusion: More than 81% of people suffering from chronic kidney disease who received percutaneous nephrolithotomy had their renal function preserved or enhanced at long-term follow-up. About 24% of these individuals experienced stone recurrence or stone development.

Key words: percutaneous, kidney, kidney calculi, nephrostomy recurrence, glomerular filtration rate