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Review Article 


Proniosome: A Strategic Approach for Improving Oral Drug Delivery

Ahmad Shahrul Mubarok, Devy Maulidya Cahyani, Muhammad Agus Syamsur Rijal, Andang Miatmoko.


Abstract
The development of drug delivery systems using nanotechnology is an effort to improve human health by enabling the effectiveness of active drug ingredients by overcoming various physicochemical characteristics through efforts to overcome solubility and bioavailability problems of active drug ingredients. Niosomes are one of the delivery systems being developed to improve the effectiveness of drug solubility, but there are several limitations in the form of physical instability, aggregation, fusion, leakage in vesicles, and hydrolysis. The development of pro-vesicles such as proniosomes, provides a breakthrough in overcoming these problems as well as being a potential alternative dosage form. Proniosomes provide a stable and scalable alternative to niosomes for expanding oral bioavailability, addressing solubility issues, and augmenting drug permeability across biological membranes.

Key words: Health and human, Drug delivery system, Nanotechnology, Niosomes, Proniosomes


 
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How to Cite this Article
Pubmed Style

Mubarok AS, Cahyani DM, Rijal MAS, Miatmoko A. Proniosome: A Strategic Approach for Improving Oral Drug Delivery. doi:10.5455/IJMRCR.172-1738545985

Web Style

Mubarok AS, Cahyani DM, Rijal MAS, Miatmoko A. Proniosome: A Strategic Approach for Improving Oral Drug Delivery. https://www.mdpub.net/?mno=240751 [Access: April 04, 2025]. doi:10.5455/IJMRCR.172-1738545985

AMA (American Medical Association) Style

Mubarok AS, Cahyani DM, Rijal MAS, Miatmoko A. Proniosome: A Strategic Approach for Improving Oral Drug Delivery. doi:10.5455/IJMRCR.172-1738545985


Vancouver/ICMJE Style

Mubarok AS, Cahyani DM, Rijal MAS, Miatmoko A. Proniosome: A Strategic Approach for Improving Oral Drug Delivery. doi:10.5455/IJMRCR.172-1738545985


Harvard Style

Mubarok, A. S., Cahyani, . D. M., Rijal, . M. A. S. & Miatmoko, . A. (0) Proniosome: A Strategic Approach for Improving Oral Drug Delivery. doi:10.5455/IJMRCR.172-1738545985


Turabian Style

Mubarok, Ahmad Shahrul, Devy Maulidya Cahyani, Muhammad Agus Syamsur Rijal, and Andang Miatmoko. 0. Proniosome: A Strategic Approach for Improving Oral Drug Delivery. doi:10.5455/IJMRCR.172-1738545985


Chicago Style

Mubarok, Ahmad Shahrul, Devy Maulidya Cahyani, Muhammad Agus Syamsur Rijal, and Andang Miatmoko. "Proniosome: A Strategic Approach for Improving Oral Drug Delivery." doi:10.5455/IJMRCR.172-1738545985


MLA (The Modern Language Association) Style

Mubarok, Ahmad Shahrul, Devy Maulidya Cahyani, Muhammad Agus Syamsur Rijal, and Andang Miatmoko. "Proniosome: A Strategic Approach for Improving Oral Drug Delivery." doi:10.5455/IJMRCR.172-1738545985


APA (American Psychological Association) Style

Mubarok, A. S., Cahyani, . D. M., Rijal, . M. A. S. & Miatmoko, . A. (0) Proniosome: A Strategic Approach for Improving Oral Drug Delivery. doi:10.5455/IJMRCR.172-1738545985


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