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Case Report
Online Published: 23 May 2018
 


Tuberculous granulomatous interstitial nephritis of solitary kidney in a renal donor

Kanakaraj Arumugham, Balaji Kirushnan, Akhil Mohammed Shujauddin, Ravichandran Rajan.


Abstract
Background:Unexplained azotaemia in a renal donor needs urgent evaluation. Renal biopsy is required when the urine examination shows proteinuria and when there is an unexplained worsening of renal functions. Granulomatous interstitial nephritis of solitary kidney in a renal donor has not been reported so far in the literature.
Case summary: We would like to report on the benefits of performing a renal biopsy of a solitary kidney in establishing a diagnosis. A 51-year old woman, who donated her kidney 15 years ago, developed azotaemia with mild proteinuria in the setting of significant weight loss of 10 kilograms in 3 months. Kidney biopsy revealed granulomatous interstitial nephritis with areas of caseating necrosis, suggestive of tuberculosis. She received first-line anti-tuberculous treatment for 9 months and her serum creatinine improved from baseline, which remained stable after 1 year.
Conclusion: Unusual causes of renal impairment needs to be considered in a patient without any obvious precipitating conditions. A kidney biopsy would help in identifying the exact cause in particular, a kidney donor, especially when a kidney biopsy is considered a relative contraindication.

Key words: Tuberculosis, Renal donor, renal biopsy, solitary kidney


 
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How to Cite this Article
Pubmed Style

Arumugham K, Kirushnan B, Shujauddin AM, Rajan R. Tuberculous granulomatous interstitial nephritis of solitary kidney in a renal donor. Int J Med Rev Case Rep. 2018; 2(3): 73-75. doi:10.5455/IJMRCR.tuberculous-granulomatous-nephritis-donor

Web Style

Arumugham K, Kirushnan B, Shujauddin AM, Rajan R. Tuberculous granulomatous interstitial nephritis of solitary kidney in a renal donor. https://www.mdpub.net/?mno=292853 [Access: October 13, 2024]. doi:10.5455/IJMRCR.tuberculous-granulomatous-nephritis-donor

AMA (American Medical Association) Style

Arumugham K, Kirushnan B, Shujauddin AM, Rajan R. Tuberculous granulomatous interstitial nephritis of solitary kidney in a renal donor. Int J Med Rev Case Rep. 2018; 2(3): 73-75. doi:10.5455/IJMRCR.tuberculous-granulomatous-nephritis-donor


Vancouver/ICMJE Style

Arumugham K, Kirushnan B, Shujauddin AM, Rajan R. Tuberculous granulomatous interstitial nephritis of solitary kidney in a renal donor. Int J Med Rev Case Rep. (2018), [cited October 13, 2024]; 2(3): 73-75. doi:10.5455/IJMRCR.tuberculous-granulomatous-nephritis-donor


Harvard Style

Arumugham, K., Kirushnan, . B., Shujauddin, . A. M. & Rajan, . R. (2018) Tuberculous granulomatous interstitial nephritis of solitary kidney in a renal donor. Int J Med Rev Case Rep, 2 (3), 73-75. doi:10.5455/IJMRCR.tuberculous-granulomatous-nephritis-donor


Turabian Style

Arumugham, Kanakaraj, Balaji Kirushnan, Akhil Mohammed Shujauddin, and Ravichandran Rajan. 2018. Tuberculous granulomatous interstitial nephritis of solitary kidney in a renal donor. International Journal of Medical Reviews and Case Reports, 2 (3), 73-75. doi:10.5455/IJMRCR.tuberculous-granulomatous-nephritis-donor


Chicago Style

Arumugham, Kanakaraj, Balaji Kirushnan, Akhil Mohammed Shujauddin, and Ravichandran Rajan. "Tuberculous granulomatous interstitial nephritis of solitary kidney in a renal donor." International Journal of Medical Reviews and Case Reports 2 (2018), 73-75. doi:10.5455/IJMRCR.tuberculous-granulomatous-nephritis-donor


MLA (The Modern Language Association) Style

Arumugham, Kanakaraj, Balaji Kirushnan, Akhil Mohammed Shujauddin, and Ravichandran Rajan. "Tuberculous granulomatous interstitial nephritis of solitary kidney in a renal donor." International Journal of Medical Reviews and Case Reports 2.3 (2018), 73-75. Print. doi:10.5455/IJMRCR.tuberculous-granulomatous-nephritis-donor


APA (American Psychological Association) Style

Arumugham, K., Kirushnan, . B., Shujauddin, . A. M. & Rajan, . R. (2018) Tuberculous granulomatous interstitial nephritis of solitary kidney in a renal donor. International Journal of Medical Reviews and Case Reports, 2 (3), 73-75. doi:10.5455/IJMRCR.tuberculous-granulomatous-nephritis-donor


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