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Original Research
Online Published: 05 May 2018
 


Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy

Dinie Ramdhani Kusuma, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, Agussalim Bukhari.


Abstract
Leprosy is chronic infectious disease caused by the intracellular parasitic pathogen Mycobacterium Leprae involves accumulation of highly reactive oxygen species (ROS) production and decreased levels of antioxidant in affected individuals. The present treatment method available for leprosy is MDT (Multi Drug Therapy) from WHO (World Health Organization) involves combination of Rifampicin, Dapsone and Clofazimine. In this cohort prospective study, we have investigated total antioxidant capacity (TAC) in 16 multibacillary leprosy patients before and after 3 months of MDT-MB WHO. In this study, we present that mean values of total antioxidant capacity (TAC) after 3 months of MDT-MB WHO were higher than before treated. From the sample groups in this study, we also found an decrease TAC levels in higher bacterial index after 3 months of MDT-MB WHO, this further increases significantly (p<0.05). Hence we conclude that 3 months giving of MDT-MB WHO increase the total antioxidant capacity.

Key words: Total antioxidant capacity (TAC), MDT-MB WHO, Leprosy MB


 
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How to Cite this Article
Pubmed Style

Kusuma DR, Amin S, Djawad K, Muchtar S, Rahmah SN, Ganda IJ, Bukhari A. Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. Int J Med Rev Case Rep. 2018; 2(4): 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy

Web Style

Kusuma DR, Amin S, Djawad K, Muchtar S, Rahmah SN, Ganda IJ, Bukhari A. Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. https://www.mdpub.net/?mno=297595 [Access: April 02, 2025]. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy

AMA (American Medical Association) Style

Kusuma DR, Amin S, Djawad K, Muchtar S, Rahmah SN, Ganda IJ, Bukhari A. Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. Int J Med Rev Case Rep. 2018; 2(4): 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy


Vancouver/ICMJE Style

Kusuma DR, Amin S, Djawad K, Muchtar S, Rahmah SN, Ganda IJ, Bukhari A. Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. Int J Med Rev Case Rep. (2018), [cited April 02, 2025]; 2(4): 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy


Harvard Style

Kusuma, D. R., Amin, . S., Djawad, . K., Muchtar, . S., Rahmah, . S. N., Ganda, . I. J. & Bukhari, . A. (2018) Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. Int J Med Rev Case Rep, 2 (4), 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy


Turabian Style

Kusuma, Dinie Ramdhani, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, and Agussalim Bukhari. 2018. Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. International Journal of Medical Reviews and Case Reports, 2 (4), 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy


Chicago Style

Kusuma, Dinie Ramdhani, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, and Agussalim Bukhari. "Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy." International Journal of Medical Reviews and Case Reports 2 (2018), 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy


MLA (The Modern Language Association) Style

Kusuma, Dinie Ramdhani, Safruddin Amin, Khairuddin Djawad, Srivitayani Muchtar, Sitti Nur Rahmah, Idham Jaya Ganda, and Agussalim Bukhari. "Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy." International Journal of Medical Reviews and Case Reports 2.4 (2018), 136-142. Print. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy


APA (American Psychological Association) Style

Kusuma, D. R., Amin, . S., Djawad, . K., Muchtar, . S., Rahmah, . S. N., Ganda, . I. J. & Bukhari, . A. (2018) Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy. International Journal of Medical Reviews and Case Reports, 2 (4), 136-142. doi:10.5455/IJMRCR.total-antioxidant-capacity-multibacillary-type-leprocy


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