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Case Series 


Osmotic Demyelination Syndrome - a case series

Krishnan Balagopal, Ajin Mohana Balachandrakumar, Elizabeth Kurian, Nimiya Sabu.

Abstract
Osmotic Demyelination Syndrome is a rare neurological condition caused by a number of clinical conditions and with a wide spectrum of clinical features. This case series describes three cases admitted to our hospital and looks at their clinical profile including aetiology, clinical features, imaging findings and outcomes after treatment. Rapid correction of sodium and alcoholism were found to be the main etiologies. Clinical presentation included symptoms like altered sensorium, dysarthria, extrapyramidal symptoms, pyramidal involvement and movement disorders. Imaging done showed symmetrical lesions involving the pons and the basal ganglia. The treatment was supportive in nature and outcomes were good in most of the cases. Early identification of this condition and treatment is key to good long-term outcomes.

Key words: Osmotic Demyelination Syndrome, Central Pontine Myelinolysis, Extrapontine Myelinolysis, Hyponatremia, Alcoholism


 
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How to Cite this Article
Pubmed Style

Balagopal K, Balachandrakumar AM, Kurian E, Sabu N. Osmotic Demyelination Syndrome - a case series. Int J Med Rev Case Rep. 2022; 6(5): 22-25. doi:10.5455/IJMRCR.OsmoticDemyelinationSyndrome


Web Style

Balagopal K, Balachandrakumar AM, Kurian E, Sabu N. Osmotic Demyelination Syndrome - a case series. https://www.mdpub.net/?mno=30680 [Access: November 19, 2022]. doi:10.5455/IJMRCR.OsmoticDemyelinationSyndrome


AMA (American Medical Association) Style

Balagopal K, Balachandrakumar AM, Kurian E, Sabu N. Osmotic Demyelination Syndrome - a case series. Int J Med Rev Case Rep. 2022; 6(5): 22-25. doi:10.5455/IJMRCR.OsmoticDemyelinationSyndrome



Vancouver/ICMJE Style

Balagopal K, Balachandrakumar AM, Kurian E, Sabu N. Osmotic Demyelination Syndrome - a case series. Int J Med Rev Case Rep. (2022), [cited November 19, 2022]; 6(5): 22-25. doi:10.5455/IJMRCR.OsmoticDemyelinationSyndrome



Harvard Style

Balagopal, K., Balachandrakumar, . A. M., Kurian, . E. & Sabu, . N. (2022) Osmotic Demyelination Syndrome - a case series. Int J Med Rev Case Rep, 6 (5), 22-25. doi:10.5455/IJMRCR.OsmoticDemyelinationSyndrome



Turabian Style

Balagopal, Krishnan, Ajin Mohana Balachandrakumar, Elizabeth Kurian, and Nimiya Sabu. 2022. Osmotic Demyelination Syndrome - a case series. International Journal of Medical Reviews and Case Reports, 6 (5), 22-25. doi:10.5455/IJMRCR.OsmoticDemyelinationSyndrome



Chicago Style

Balagopal, Krishnan, Ajin Mohana Balachandrakumar, Elizabeth Kurian, and Nimiya Sabu. "Osmotic Demyelination Syndrome - a case series." International Journal of Medical Reviews and Case Reports 6 (2022), 22-25. doi:10.5455/IJMRCR.OsmoticDemyelinationSyndrome



MLA (The Modern Language Association) Style

Balagopal, Krishnan, Ajin Mohana Balachandrakumar, Elizabeth Kurian, and Nimiya Sabu. "Osmotic Demyelination Syndrome - a case series." International Journal of Medical Reviews and Case Reports 6.5 (2022), 22-25. Print. doi:10.5455/IJMRCR.OsmoticDemyelinationSyndrome



APA (American Psychological Association) Style

Balagopal, K., Balachandrakumar, . A. M., Kurian, . E. & Sabu, . N. (2022) Osmotic Demyelination Syndrome - a case series. International Journal of Medical Reviews and Case Reports, 6 (5), 22-25. doi:10.5455/IJMRCR.OsmoticDemyelinationSyndrome