Abstract
Introduction: Central nervous system (CNS) tumours are a diverse group of neoplasms and the most dreaded form of cancer with high morbidity and mortality comprising less than 2% of all malignancies. Not much is known about the epidemiology of CNS tumours in our population in North-East India.

Aim: Aim of this study is to identify the age groups, gender distribution, topography and different histological types of CNS tumours and classify them.
Materials and Methods: This retrospective histopathological analysis of brain tumours was carried out in the Department of Pathology, Agartala Government Medical College, Tripura, India, from May 2019 to June 2021. During this period, a total of 42 neurosurgical biopsies were retrieved from the archives of the department. The diagnoses in all the cases were made on histopathological examination of routinely processed tissue. The hematoxylin and eosin-stained sections in all cases were reviewed by the authors, and the diagnosis was confirmed applying the WHO classification 2016. The relative frequency of tumours and the distribution as per age, sex, and location of the lesion were analyzed. A wide range of histopathological spectrum of CNS tumours was observed and was classified according to the WHO classification system of 2016. The primary CNS tumours were graded from Grade I to Grade 1V.
Results and Conclusion: There were 39(92.8%) cases of primary tumours and 3(7.2%) cases were metastatic tumours. Overall meningioma was the most common tumour (48%) followed by glioblastoma (21.5%). Males are more affected compared to females. However WHO grade I neoplasm was the predominant (46%). The present study helps to provide information regarding the burden of disease in our population.

Key words: CNS tumours, Brain tumours, Meningioma, North East India