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Original Research
Online Published: 03 Oct 2021
 


Comparison of cerumen and ofloxacin ear drops bactericidal tests against staphylococcus aureus and pseudomonas aeruginosa bacteria

Komang Andi Dwi Saputra, Eka Putra Setiawan, I Putu Yupindra Pradiptha.


Abstract
Background: Cerumen or earwax is a mixture of sebaceous gland secretions (fat) and apocrine (ceruminous) glands with epithelial debris. This combination of compositions forms an acidic layer (normal pH of 6.8), which helps prevent infection of the ear canal. Cerumen contains various antimicrobial factors, which also prevent infection.
This study aims to compare bactericidal activity on cerumen and ofloxacin in vitro in Staphylococcus aureus and Pseudomonas aeruginosa.
Method: The study used a type of in vitro laboratory experimental research to compare bactericidal activity in cerumen and ofloxacin drops against Staphylococcus aureus and Pseudomonas aeruginosa.
Result: Based on the results of research for Staphylococcus aureus bacteria, the average inhibition capability of cerumen was 0.7 ± 2.1 mm. While the average inhibition capability of ofloxacin was 32.9 ± 0.9 mm.
For the bacterium Pseudomonas aeruginosa, the average inhibition capability of cerumen is 0 ± 0 mm. While the average inhibition capability of ofloxacin was 31.3 ± 0.5 mm. Both variables show significant differences because both have a p-value lower than p <0.05.
Conclusion: There are differences in inhibition capability of cerumen and ofloxacin eardrops against Staphylococcus aureus and Pseudomonas aeruginosa bacteria.

Key words: Bactericidal, Cerumen, In-vitro, Pseudomonas aeruginosa, Staphylococcus aureus


 
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How to Cite this Article
Pubmed Style

Saputra KAD, Setiawan EP, Pradiptha IPY. Comparison of cerumen and ofloxacin ear drops bactericidal tests against staphylococcus aureus and pseudomonas aeruginosa bacteria. Int J Med Rev Case Rep. 2021; 5(9): 57-60. doi:10.5455/IJMRCR.cerumen-ofloxacin-ear-drops

Web Style

Saputra KAD, Setiawan EP, Pradiptha IPY. Comparison of cerumen and ofloxacin ear drops bactericidal tests against staphylococcus aureus and pseudomonas aeruginosa bacteria. https://www.mdpub.net/?mno=33912 [Access: October 14, 2024]. doi:10.5455/IJMRCR.cerumen-ofloxacin-ear-drops

AMA (American Medical Association) Style

Saputra KAD, Setiawan EP, Pradiptha IPY. Comparison of cerumen and ofloxacin ear drops bactericidal tests against staphylococcus aureus and pseudomonas aeruginosa bacteria. Int J Med Rev Case Rep. 2021; 5(9): 57-60. doi:10.5455/IJMRCR.cerumen-ofloxacin-ear-drops


Vancouver/ICMJE Style

Saputra KAD, Setiawan EP, Pradiptha IPY. Comparison of cerumen and ofloxacin ear drops bactericidal tests against staphylococcus aureus and pseudomonas aeruginosa bacteria. Int J Med Rev Case Rep. (2021), [cited October 14, 2024]; 5(9): 57-60. doi:10.5455/IJMRCR.cerumen-ofloxacin-ear-drops


Harvard Style

Saputra, K. A. D., Setiawan, . E. P. & Pradiptha, . I. P. Y. (2021) Comparison of cerumen and ofloxacin ear drops bactericidal tests against staphylococcus aureus and pseudomonas aeruginosa bacteria. Int J Med Rev Case Rep, 5 (9), 57-60. doi:10.5455/IJMRCR.cerumen-ofloxacin-ear-drops


Turabian Style

Saputra, Komang Andi Dwi, Eka Putra Setiawan, and I Putu Yupindra Pradiptha. 2021. Comparison of cerumen and ofloxacin ear drops bactericidal tests against staphylococcus aureus and pseudomonas aeruginosa bacteria. International Journal of Medical Reviews and Case Reports, 5 (9), 57-60. doi:10.5455/IJMRCR.cerumen-ofloxacin-ear-drops


Chicago Style

Saputra, Komang Andi Dwi, Eka Putra Setiawan, and I Putu Yupindra Pradiptha. "Comparison of cerumen and ofloxacin ear drops bactericidal tests against staphylococcus aureus and pseudomonas aeruginosa bacteria." International Journal of Medical Reviews and Case Reports 5 (2021), 57-60. doi:10.5455/IJMRCR.cerumen-ofloxacin-ear-drops


MLA (The Modern Language Association) Style

Saputra, Komang Andi Dwi, Eka Putra Setiawan, and I Putu Yupindra Pradiptha. "Comparison of cerumen and ofloxacin ear drops bactericidal tests against staphylococcus aureus and pseudomonas aeruginosa bacteria." International Journal of Medical Reviews and Case Reports 5.9 (2021), 57-60. Print. doi:10.5455/IJMRCR.cerumen-ofloxacin-ear-drops


APA (American Psychological Association) Style

Saputra, K. A. D., Setiawan, . E. P. & Pradiptha, . I. P. Y. (2021) Comparison of cerumen and ofloxacin ear drops bactericidal tests against staphylococcus aureus and pseudomonas aeruginosa bacteria. International Journal of Medical Reviews and Case Reports, 5 (9), 57-60. doi:10.5455/IJMRCR.cerumen-ofloxacin-ear-drops


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