E-ISSN 2534-9821
 

Review Article 


Microspheres for Inhalation Delivery (Characteristics and In Vitro Release)

Noorma Rosita, Tekla Kalalo, Andang Miatmoko, Yashwant Pathak, Dewi Melani Hariyadi.

Abstract
Background: Microspheres are one of the potential lung delivery systems for lungs and respiratory diseases because of their ability to encapsulate various types of drugs, biocompatibility, high bioavailability, protect drugs from environmental effects such as humidity, heat, oxidation, and can release drugs in a sustained or prolonged release. The suitability of microspheres to be delivered by inhalation is determined by the characteristics and release of the drugs from the microspheres. The characterization and release study of microspheres is influenced by several factors such as the type of polymer used, polymer concentration, polymer ratio, type of crosslinker, the concentration of crosslinker, and method of encapsulation.
Methods of review: This scoping review consists of 32 publications from the periods between 2007 and 2021. Publications were extracted from a search engine using various keywords. Data of publications that met the criteria were extracted manually.
Conclusions: This review focuses on the characteristics and release of microspheres for inhalation using polymers and various encapsulation methods.

Key words: Microspheres, inhalation, characteristics, in vitro release, respiratory diseases


 
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How to Cite this Article
Pubmed Style

Rosita N, Kalalo T, Miatmoko A, Pathak Y, Hariyadi DM. Microspheres for Inhalation Delivery (Characteristics and In Vitro Release). Int J Med Rev Case Rep. 2022; 6(2): 24-31. doi:10.5455/IJMRCR.MicrospheresforInhalationDelivery


Web Style

Rosita N, Kalalo T, Miatmoko A, Pathak Y, Hariyadi DM. Microspheres for Inhalation Delivery (Characteristics and In Vitro Release). https://www.mdpub.net/?mno=39825 [Access: January 14, 2023]. doi:10.5455/IJMRCR.MicrospheresforInhalationDelivery


AMA (American Medical Association) Style

Rosita N, Kalalo T, Miatmoko A, Pathak Y, Hariyadi DM. Microspheres for Inhalation Delivery (Characteristics and In Vitro Release). Int J Med Rev Case Rep. 2022; 6(2): 24-31. doi:10.5455/IJMRCR.MicrospheresforInhalationDelivery



Vancouver/ICMJE Style

Rosita N, Kalalo T, Miatmoko A, Pathak Y, Hariyadi DM. Microspheres for Inhalation Delivery (Characteristics and In Vitro Release). Int J Med Rev Case Rep. (2022), [cited January 14, 2023]; 6(2): 24-31. doi:10.5455/IJMRCR.MicrospheresforInhalationDelivery



Harvard Style

Rosita, N., Kalalo, . T., Miatmoko, . A., Pathak, . Y. & Hariyadi, . D. M. (2022) Microspheres for Inhalation Delivery (Characteristics and In Vitro Release). Int J Med Rev Case Rep, 6 (2), 24-31. doi:10.5455/IJMRCR.MicrospheresforInhalationDelivery



Turabian Style

Rosita, Noorma, Tekla Kalalo, Andang Miatmoko, Yashwant Pathak, and Dewi Melani Hariyadi. 2022. Microspheres for Inhalation Delivery (Characteristics and In Vitro Release). International Journal of Medical Reviews and Case Reports, 6 (2), 24-31. doi:10.5455/IJMRCR.MicrospheresforInhalationDelivery



Chicago Style

Rosita, Noorma, Tekla Kalalo, Andang Miatmoko, Yashwant Pathak, and Dewi Melani Hariyadi. "Microspheres for Inhalation Delivery (Characteristics and In Vitro Release)." International Journal of Medical Reviews and Case Reports 6 (2022), 24-31. doi:10.5455/IJMRCR.MicrospheresforInhalationDelivery



MLA (The Modern Language Association) Style

Rosita, Noorma, Tekla Kalalo, Andang Miatmoko, Yashwant Pathak, and Dewi Melani Hariyadi. "Microspheres for Inhalation Delivery (Characteristics and In Vitro Release)." International Journal of Medical Reviews and Case Reports 6.2 (2022), 24-31. Print. doi:10.5455/IJMRCR.MicrospheresforInhalationDelivery



APA (American Psychological Association) Style

Rosita, N., Kalalo, . T., Miatmoko, . A., Pathak, . Y. & Hariyadi, . D. M. (2022) Microspheres for Inhalation Delivery (Characteristics and In Vitro Release). International Journal of Medical Reviews and Case Reports, 6 (2), 24-31. doi:10.5455/IJMRCR.MicrospheresforInhalationDelivery