E-ISSN 2534-9821
 

Original Article
Online Published: 27 Jul 2019
 


Association between bacterial colonization and serum level of interleukin-8 in stable chronic obstructive pulmonary disease in Makassar

Stephanie Susantyo, Muhammad Ilyas, Syakib Bakri, Wasis Udaya, Hasyim Kasim, Faridin Pango, Harun Iskandar, Arifin Seweng.


Abstract
Background: Chronic Obstructive Pulmonary Disease is a chronic inflammatory disease due to particles or toxic gases exposure that occur in a long time. Chronic inflammation of the airways and lung damage facilitates the colonization of bacterial pathogen in the lower airways of patients with stable chronic obstructive pulmonary disease. The bacteria in the lower airway activate the immune system by stimulating inflammatory cells, cytokines, proinflammation and chemokine (Interleukin-8).1 Objective: Determined the correlation between bacterial colonization and serum level of interleukin-8 in stable chronic obstructive pulmonary disease at Wahidin Sudirohusodo Hospital Makassar and its network. Methods: The study design was analytical study with a cross sectional design. Subjects were 61 subjects with stable chronic obstructive pulmonary disease who were examined for sputum culture and serum levels of interleukin-8. Results: The mean of serum interleukin-8 level was significantly higher in negative-gram bacterial colonization compared to positive-gram bacterial colonization and no bacterial growth (p <0.05). Conclusion: There is a correlation between bacterial colonization and serum levels of interleukin-8 in stable chronic obstructive pulmonary disease.

Key words: Stable chronic obstructive pulmonary disease, Sputum culture, Interleukin-8


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Stephanie Susantyo
Articles by Muhammad Ilyas
Articles by Syakib Bakri
Articles by Wasis Udaya
Articles by Hasyim Kasim
Articles by Faridin Pango
Articles by Harun Iskandar
Articles by Arifin Seweng
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Susantyo S, MI, Bakri S, Udaya W, Kasim H, Pango F, Iskandar H, Seweng A. Association between bacterial colonization and serum level of interleukin-8 in stable chronic obstructive pulmonary disease in Makassar. Int J Med Rev Case Rep. 2019; 3(11): 707-710. doi:10.5455/IJMRCR.correlation-bacterial-colonization-il-8


Web Style

Susantyo S, MI, Bakri S, Udaya W, Kasim H, Pango F, Iskandar H, Seweng A. Association between bacterial colonization and serum level of interleukin-8 in stable chronic obstructive pulmonary disease in Makassar. https://www.mdpub.net/?mno=42491 [Access: October 13, 2024]. doi:10.5455/IJMRCR.correlation-bacterial-colonization-il-8


AMA (American Medical Association) Style

Susantyo S, MI, Bakri S, Udaya W, Kasim H, Pango F, Iskandar H, Seweng A. Association between bacterial colonization and serum level of interleukin-8 in stable chronic obstructive pulmonary disease in Makassar. Int J Med Rev Case Rep. 2019; 3(11): 707-710. doi:10.5455/IJMRCR.correlation-bacterial-colonization-il-8



Vancouver/ICMJE Style

Susantyo S, MI, Bakri S, Udaya W, Kasim H, Pango F, Iskandar H, Seweng A. Association between bacterial colonization and serum level of interleukin-8 in stable chronic obstructive pulmonary disease in Makassar. Int J Med Rev Case Rep. (2019), [cited October 13, 2024]; 3(11): 707-710. doi:10.5455/IJMRCR.correlation-bacterial-colonization-il-8



Harvard Style

Susantyo, S., , . M. I., Bakri, . S., Udaya, . W., Kasim, . H., Pango, . F., Iskandar, . H. & Seweng, . A. (2019) Association between bacterial colonization and serum level of interleukin-8 in stable chronic obstructive pulmonary disease in Makassar. Int J Med Rev Case Rep, 3 (11), 707-710. doi:10.5455/IJMRCR.correlation-bacterial-colonization-il-8



Turabian Style

Susantyo, Stephanie, Muhammad Ilyas, Syakib Bakri, Wasis Udaya, Hasyim Kasim, Faridin Pango, Harun Iskandar, and Arifin Seweng. 2019. Association between bacterial colonization and serum level of interleukin-8 in stable chronic obstructive pulmonary disease in Makassar. International Journal of Medical Reviews and Case Reports, 3 (11), 707-710. doi:10.5455/IJMRCR.correlation-bacterial-colonization-il-8



Chicago Style

Susantyo, Stephanie, Muhammad Ilyas, Syakib Bakri, Wasis Udaya, Hasyim Kasim, Faridin Pango, Harun Iskandar, and Arifin Seweng. "Association between bacterial colonization and serum level of interleukin-8 in stable chronic obstructive pulmonary disease in Makassar." International Journal of Medical Reviews and Case Reports 3 (2019), 707-710. doi:10.5455/IJMRCR.correlation-bacterial-colonization-il-8



MLA (The Modern Language Association) Style

Susantyo, Stephanie, Muhammad Ilyas, Syakib Bakri, Wasis Udaya, Hasyim Kasim, Faridin Pango, Harun Iskandar, and Arifin Seweng. "Association between bacterial colonization and serum level of interleukin-8 in stable chronic obstructive pulmonary disease in Makassar." International Journal of Medical Reviews and Case Reports 3.11 (2019), 707-710. Print. doi:10.5455/IJMRCR.correlation-bacterial-colonization-il-8



APA (American Psychological Association) Style

Susantyo, S., , . M. I., Bakri, . S., Udaya, . W., Kasim, . H., Pango, . F., Iskandar, . H. & Seweng, . A. (2019) Association between bacterial colonization and serum level of interleukin-8 in stable chronic obstructive pulmonary disease in Makassar. International Journal of Medical Reviews and Case Reports, 3 (11), 707-710. doi:10.5455/IJMRCR.correlation-bacterial-colonization-il-8