Obesity Effect on Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Value in Various Metabolic Syndrome (MS) Components

Syahrir  Parawansyah; Husaini Umar; Makbul Aman Mansyur; Syakib Bakri; Hasyim Kasim; Himawan Sanusi; Rahmawati Minhajat; Arifin Seweng

doi:10.5455/IJMRCR.Obesity-Effect-on-HOMA-IR-Value

2023, Vol: 7, Issue: 11

7 / 11Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Required files to be uploaded

Copyright Transfer Form

« Previous Article

Original Research
Online Published: 11 Aug 2019

Int J Med Rev Case Rep. 2019; 3(11): 671-675

doi: 10.5455/IJMRCR.Obesity-Effect-on-HOMA-IR-Value

Obesity Effect on Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Value in Various Metabolic Syndrome (MS) Components

Syahrir Parawansyah, Husaini Umar, Makbul Aman Mansyur, Syakib Bakri, Hasyim Kasim, Himawan Sanusi, Rahmawati Minhajat, Arifin Seweng.

Abstract
Insulin resistance plays a major role in the pathophysiology of MS. HOMA-IR has proven to be a strong examination to assess insulin resistance. Differences in the prevalence of the MS are also caused by the diagnostic criteria used. Obesity is an absolute requirement for the criteria for MS according to the IDF compared to other components, while NCEP ATP III only requires the number of components. The purpose of this study was to determine the effect of obesity on HOMA-IR values on various components of the MS. The study was cross sectional, in healthy male subjects aged 40-65 years. The research was conducted at various health facilities in Makassar. Subjects were assessed for blood pressure, abdominal circumference, fasting blood sugar, HDL cholesterol, triglycerides and HOMA-IR. Tertile 3 HOMA-IR is considered as insulin resistance. Then the samples were divided into 5 groups based on obesity and the number of MS components (including the NCEP ATP III and IDF criteria) and compared each HOMA-IR with the non-obese + group without other MS components (reference group). Of the total 102 samples that took part in the study, the increase in proportion of subjects suffering from insulin resistance was in accordance with the number of components of MS that were disrupted and the presence of obesity. HOMA-IR values in Obese subjects + 2-4 components of the MS were significantly higher than the reference group. HOMA-IR values in Obese + 0-1 subjects in the MS component were significantly higher than the reference group, and HOMA-IR values in Non-Obese + 1- 3 subjects in the MS were not significantly different from the reference group. Obesity (whether accompanied by or without other components of the MS) is very influential on the value of HOMA-IR.

Key words: Obesity, HOMA-IR, Metabolic Syndrome

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Syahrir Parawansyah Articles by Husaini Umar Articles by Makbul Aman Mansyur Articles by Syakib Bakri Articles by Hasyim Kasim Articles by Himawan Sanusi Articles by Rahmawati Minhajat Articles by Arifin Seweng
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

SP, Umar H, Mansyur MA, Bakri S, Kasim H, Sanusi H, Minhajat R, Seweng A, . Obesity Effect on Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Value in Various Metabolic Syndrome (MS) Components. Int J Med Rev Case Rep. 2019; 3(11): 671-675. doi:10.5455/IJMRCR.Obesity-Effect-on-HOMA-IR-Value

Web Style

SP, Umar H, Mansyur MA, Bakri S, Kasim H, Sanusi H, Minhajat R, Seweng A, . Obesity Effect on Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Value in Various Metabolic Syndrome (MS) Components. https://www.mdpub.net/?mno=43563 [Access: October 13, 2024]. doi:10.5455/IJMRCR.Obesity-Effect-on-HOMA-IR-Value

AMA (American Medical Association) Style

SP, Umar H, Mansyur MA, Bakri S, Kasim H, Sanusi H, Minhajat R, Seweng A, . Obesity Effect on Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Value in Various Metabolic Syndrome (MS) Components. Int J Med Rev Case Rep. 2019; 3(11): 671-675. doi:10.5455/IJMRCR.Obesity-Effect-on-HOMA-IR-Value

Vancouver/ICMJE Style

SP, Umar H, Mansyur MA, Bakri S, Kasim H, Sanusi H, Minhajat R, Seweng A, . Obesity Effect on Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Value in Various Metabolic Syndrome (MS) Components. Int J Med Rev Case Rep. (2019), [cited October 13, 2024]; 3(11): 671-675. doi:10.5455/IJMRCR.Obesity-Effect-on-HOMA-IR-Value

Harvard Style

, S. P., Umar, H., Mansyur, M. A., Bakri, S., Kasim, H., Sanusi, H., Minhajat, R., Seweng, A. & (2019) Obesity Effect on Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Value in Various Metabolic Syndrome (MS) Components. Int J Med Rev Case Rep, 3 (11), 671-675. doi:10.5455/IJMRCR.Obesity-Effect-on-HOMA-IR-Value

Turabian Style

, Syahrir Parawansyah, Husaini Umar, Makbul Aman Mansyur, Syakib Bakri, Hasyim Kasim, Himawan Sanusi, Rahmawati Minhajat, Arifin Seweng, and . 2019. Obesity Effect on Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Value in Various Metabolic Syndrome (MS) Components. International Journal of Medical Reviews and Case Reports, 3 (11), 671-675. doi:10.5455/IJMRCR.Obesity-Effect-on-HOMA-IR-Value

Chicago Style

, Syahrir Parawansyah, Husaini Umar, Makbul Aman Mansyur, Syakib Bakri, Hasyim Kasim, Himawan Sanusi, Rahmawati Minhajat, Arifin Seweng, and . "Obesity Effect on Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Value in Various Metabolic Syndrome (MS) Components." International Journal of Medical Reviews and Case Reports 3 (2019), 671-675. doi:10.5455/IJMRCR.Obesity-Effect-on-HOMA-IR-Value

MLA (The Modern Language Association) Style

, Syahrir Parawansyah, Husaini Umar, Makbul Aman Mansyur, Syakib Bakri, Hasyim Kasim, Himawan Sanusi, Rahmawati Minhajat, Arifin Seweng, and . "Obesity Effect on Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Value in Various Metabolic Syndrome (MS) Components." International Journal of Medical Reviews and Case Reports 3.11 (2019), 671-675. Print. doi:10.5455/IJMRCR.Obesity-Effect-on-HOMA-IR-Value

APA (American Psychological Association) Style

, S. P., Umar, H., Mansyur, M. A., Bakri, S., Kasim, H., Sanusi, H., Minhajat, R., Seweng, A. & (2019) Obesity Effect on Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Value in Various Metabolic Syndrome (MS) Components. International Journal of Medical Reviews and Case Reports, 3 (11), 671-675. doi:10.5455/IJMRCR.Obesity-Effect-on-HOMA-IR-Value

About International Journal of Medical Reviews and Case Reports

International Journal of Medical Reviews and Case Reports (Int J Med Rev Case Rep)ISSN: 2534-9821The International Journal of Medical Reviews and Ca ... Read more.

For best results, please use Internet Explorer or Google Chrome.

Contact Information

Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the International Journal of Medical Reviews and Case Reports editorial office as follows:

Bulgarian Association of Young Surgeons (BAYS);

National Center of Public Health and Analyses (NCPHA), floor 2, office № 31, Sofia 1431, Bulgaria.

inkov@journalmedica.com

Financial department is managed by International Sci Ink Press.

It is a company registered in Bulgaria with registered no. 205414288 and registered address at 57 Antim I str., Vazrazhdane, Sofia, 1303, Bulgaria.

Tel: +359883427500

About International Journal of Medical Reviews and Case Reports

Contact Information

How to cite this article