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Case Report
Online Published: 11 Sep 2022
 


Kikuchi-Fujimoto disease. (Histiocytic necrotizing lymphadenitis): The case report of a rare disease.

Sujan Narayan Agrawal.


Abstract
Introduction: The Kikuchi-Fujimoto disease (KFD), also called histiocytic necrotizing lymphadenitis, is a benign, self-limiting disease of lymph nodes. It is a disease of unknown aetiology, and it causes cervical lymphadenitis. It predominantly affects young women. It closely mimics an infective, neoplastic or autoimmune disorder. Case report: Here, we present a case of a 28-year female having enlarged cervical and axillary lymph nodes. She had a fever, rash, and arthralgia. Fine needle aspiration cytology (FNAC) was reported reactive lymphadenitis, and the patient started on antibiotics. The response was unsatisfactory, so further investigations were done, including workup for tuberculosis and lymphomas. Histopathology and immunohistochemistry suggested the diagnosis of Kikuchi's disease. She responded well to symptomatic treatment. Conclusion: The paper highlights a rare disease entity, i.e., Kikuchi-Fujimoto disease. The presentation is misleading; unless the clinician knows this disease, it involves unnecessary investigations and treatment.

Key words: Kikuchi-Fujimoto disease, Histiocytic Necrotizing Lymphadenitis, Systemic Lupus Erythematosus (SLE), Immunohistochemistry


 
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Pubmed Style

Sujan Narayan Agrawal. Kikuchi-Fujimoto disease. (Histiocytic necrotizing lymphadenitis): The case report of a rare disease.. Int J Med Rev Case Rep. 2022; 6(22): 7-10. doi:10.5455/IJMRCR.Kikuchi-Fujimotodisease-CASE-1

Web Style

Sujan Narayan Agrawal. Kikuchi-Fujimoto disease. (Histiocytic necrotizing lymphadenitis): The case report of a rare disease.. https://www.mdpub.net/?mno=63385 [Access: April 02, 2025]. doi:10.5455/IJMRCR.Kikuchi-Fujimotodisease-CASE-1

AMA (American Medical Association) Style

Sujan Narayan Agrawal. Kikuchi-Fujimoto disease. (Histiocytic necrotizing lymphadenitis): The case report of a rare disease.. Int J Med Rev Case Rep. 2022; 6(22): 7-10. doi:10.5455/IJMRCR.Kikuchi-Fujimotodisease-CASE-1


Vancouver/ICMJE Style

Sujan Narayan Agrawal. Kikuchi-Fujimoto disease. (Histiocytic necrotizing lymphadenitis): The case report of a rare disease.. Int J Med Rev Case Rep. (2022), [cited April 02, 2025]; 6(22): 7-10. doi:10.5455/IJMRCR.Kikuchi-Fujimotodisease-CASE-1


Harvard Style

Sujan Narayan Agrawal (2022) Kikuchi-Fujimoto disease. (Histiocytic necrotizing lymphadenitis): The case report of a rare disease.. Int J Med Rev Case Rep, 6 (22), 7-10. doi:10.5455/IJMRCR.Kikuchi-Fujimotodisease-CASE-1


Turabian Style

Sujan Narayan Agrawal. 2022. Kikuchi-Fujimoto disease. (Histiocytic necrotizing lymphadenitis): The case report of a rare disease.. International Journal of Medical Reviews and Case Reports, 6 (22), 7-10. doi:10.5455/IJMRCR.Kikuchi-Fujimotodisease-CASE-1


Chicago Style

Sujan Narayan Agrawal. "Kikuchi-Fujimoto disease. (Histiocytic necrotizing lymphadenitis): The case report of a rare disease.." International Journal of Medical Reviews and Case Reports 6 (2022), 7-10. doi:10.5455/IJMRCR.Kikuchi-Fujimotodisease-CASE-1


MLA (The Modern Language Association) Style

Sujan Narayan Agrawal. "Kikuchi-Fujimoto disease. (Histiocytic necrotizing lymphadenitis): The case report of a rare disease.." International Journal of Medical Reviews and Case Reports 6.22 (2022), 7-10. Print. doi:10.5455/IJMRCR.Kikuchi-Fujimotodisease-CASE-1


APA (American Psychological Association) Style

Sujan Narayan Agrawal (2022) Kikuchi-Fujimoto disease. (Histiocytic necrotizing lymphadenitis): The case report of a rare disease.. International Journal of Medical Reviews and Case Reports, 6 (22), 7-10. doi:10.5455/IJMRCR.Kikuchi-Fujimotodisease-CASE-1


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