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Review Article
Online Published: 19 Jul 2021
 


Diagnostic and Prognostic Value of Procalcitonin for Bacterial Infection in the Elderly

Nur Chandra Bunawan, Aulia Rizka.


Abstract
Bacterial infections in the elderly are deadly if late detected. Several age-related immunological changes make this population more prone to infection and have atypical presentation when infected. Biomarkers are commonly used to aid in the diagnosis of bacterial infection in the elderly given their subtle clinical presentation. However, traditional biomarkers such as leukocyte, Erythrocyte Sedimentation Rate (ESR), and C-Reactive Protein (CRP) lack specificity and some biomarkers levels are influenced by medication use. Procalcitonin, a preprocalcitonin derivative, is found to be elevated in the presence of bacterial infection and not affected by immunosuppressive drugs. Procalcitonin is a promising marker for detecting bacterial infection in the elderly. This review tries to describe the rationale and value of procalcitonin to diagnose and prognosticate bacterial infection in the elderly.

Key words: Procalcitonin, Elderly, Bacterial Infection, Diagnostic


 
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How to Cite this Article
Pubmed Style

Bunawan NC, Rizka A. Diagnostic and Prognostic Value of Procalcitonin for Bacterial Infection in the Elderly. Int J Med Rev Case Rep. 2021; 5(8): 14-18. doi:10.5455/IJMRCR.Procalcitonin-Bacterial-Infection

Web Style

Bunawan NC, Rizka A. Diagnostic and Prognostic Value of Procalcitonin for Bacterial Infection in the Elderly. https://www.mdpub.net/?mno=67998 [Access: October 13, 2024]. doi:10.5455/IJMRCR.Procalcitonin-Bacterial-Infection

AMA (American Medical Association) Style

Bunawan NC, Rizka A. Diagnostic and Prognostic Value of Procalcitonin for Bacterial Infection in the Elderly. Int J Med Rev Case Rep. 2021; 5(8): 14-18. doi:10.5455/IJMRCR.Procalcitonin-Bacterial-Infection


Vancouver/ICMJE Style

Bunawan NC, Rizka A. Diagnostic and Prognostic Value of Procalcitonin for Bacterial Infection in the Elderly. Int J Med Rev Case Rep. (2021), [cited October 13, 2024]; 5(8): 14-18. doi:10.5455/IJMRCR.Procalcitonin-Bacterial-Infection


Harvard Style

Bunawan, N. C. & Rizka, . A. (2021) Diagnostic and Prognostic Value of Procalcitonin for Bacterial Infection in the Elderly. Int J Med Rev Case Rep, 5 (8), 14-18. doi:10.5455/IJMRCR.Procalcitonin-Bacterial-Infection


Turabian Style

Bunawan, Nur Chandra, and Aulia Rizka. 2021. Diagnostic and Prognostic Value of Procalcitonin for Bacterial Infection in the Elderly. International Journal of Medical Reviews and Case Reports, 5 (8), 14-18. doi:10.5455/IJMRCR.Procalcitonin-Bacterial-Infection


Chicago Style

Bunawan, Nur Chandra, and Aulia Rizka. "Diagnostic and Prognostic Value of Procalcitonin for Bacterial Infection in the Elderly." International Journal of Medical Reviews and Case Reports 5 (2021), 14-18. doi:10.5455/IJMRCR.Procalcitonin-Bacterial-Infection


MLA (The Modern Language Association) Style

Bunawan, Nur Chandra, and Aulia Rizka. "Diagnostic and Prognostic Value of Procalcitonin for Bacterial Infection in the Elderly." International Journal of Medical Reviews and Case Reports 5.8 (2021), 14-18. Print. doi:10.5455/IJMRCR.Procalcitonin-Bacterial-Infection


APA (American Psychological Association) Style

Bunawan, N. C. & Rizka, . A. (2021) Diagnostic and Prognostic Value of Procalcitonin for Bacterial Infection in the Elderly. International Journal of Medical Reviews and Case Reports, 5 (8), 14-18. doi:10.5455/IJMRCR.Procalcitonin-Bacterial-Infection


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