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Online Publishing Date:
06 / 01 / 2023

 


To evaluate the impact of lignocaine and dexmedetomidine on hemodynamic reactions and airway reflexes during tracheal extubation in patients having laparoscopic operations

Avijeet Swain, Yangyasmit Mohanty, Girija Shankar Prasad Patro, Kanhu Charan Patro.


Abstract
Background: Endotracheal extubation is connected to airway and cardiovascular reactions that can result in tachycardia, hypertension, arrhythmias, myocardial ischemia, coughing, agitation, bronchospasm, increased haemorrhaging, and raised intracranial and intraocular pressure, all of which can be life-threatening, especially in weaker patients. These effects are observed to be attenuated by dexmedetomidine, a highly selective 2 adrenoreceptor agonist, which also provides a smooth extubation.
Aim: To evaluate the impact of dexmedetomidine following tracheal extubation on hemodynamic and ventilatory recovery.
Methods: 40 patients who matched the inclusion and exclusion criteria and were between the ages of 21 and 46 were divided randomly into two groups of 20 each for this comparative study. 90 ml of NS were given to one group, while 0.4 mg of Dexmedetomidine were given to the other. At various points throughout the entire operation, the hemodynamic parameters of the two groups were compared to check for any variations.
Results: Compared to the control group, the study group had better control over variables such mean arterial pressure, systolic blood pressure, diastolic blood pressure, and heart rate. It is the statistical significance (P < 0.002) that the extubation quality score differed between the control and dexmedetomidine groups (2.13 vs. 1.23). Cough was present in 14.27% of the study group but in 52.38% of the control group. The study population had considerably more Bradycardia and Hypertension.
Conclusion: Dexmedetomidine is administered just prior to extubation to guarantee a smooth procedure and to lessen cardiovascular reactions. Additionally, it offers sufficient postoperative sedation.

Key words: extubation, adrenoreceptor, dexmedetomidine, hemodynamic parameters


 
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How to Cite this Article
Pubmed Style

Swain A, Mohanty Y, Patro GSP, Patro KC. To evaluate the impact of lignocaine and dexmedetomidine on hemodynamic reactions and airway reflexes during tracheal extubation in patients having laparoscopic operations. Int J Med Rev Case Rep. 2022; 6(20): 14-17. doi:10.5455/IJMRCR.172-1669715965

Web Style

Swain A, Mohanty Y, Patro GSP, Patro KC. To evaluate the impact of lignocaine and dexmedetomidine on hemodynamic reactions and airway reflexes during tracheal extubation in patients having laparoscopic operations. https://www.mdpub.net/?mno=7801 [Access: April 04, 2024]. doi:10.5455/IJMRCR.172-1669715965

AMA (American Medical Association) Style

Swain A, Mohanty Y, Patro GSP, Patro KC. To evaluate the impact of lignocaine and dexmedetomidine on hemodynamic reactions and airway reflexes during tracheal extubation in patients having laparoscopic operations. Int J Med Rev Case Rep. 2022; 6(20): 14-17. doi:10.5455/IJMRCR.172-1669715965


Vancouver/ICMJE Style

Swain A, Mohanty Y, Patro GSP, Patro KC. To evaluate the impact of lignocaine and dexmedetomidine on hemodynamic reactions and airway reflexes during tracheal extubation in patients having laparoscopic operations. Int J Med Rev Case Rep. (2022), [cited April 04, 2024]; 6(20): 14-17. doi:10.5455/IJMRCR.172-1669715965


Harvard Style

Swain, A., Mohanty, . Y., Patro, . G. S. P. & Patro, . K. C. (2022) To evaluate the impact of lignocaine and dexmedetomidine on hemodynamic reactions and airway reflexes during tracheal extubation in patients having laparoscopic operations. Int J Med Rev Case Rep, 6 (20), 14-17. doi:10.5455/IJMRCR.172-1669715965


Turabian Style

Swain, Avijeet, Yangyasmit Mohanty, Girija Shankar Prasad Patro, and Kanhu Charan Patro. 2022. To evaluate the impact of lignocaine and dexmedetomidine on hemodynamic reactions and airway reflexes during tracheal extubation in patients having laparoscopic operations. International Journal of Medical Reviews and Case Reports, 6 (20), 14-17. doi:10.5455/IJMRCR.172-1669715965


Chicago Style

Swain, Avijeet, Yangyasmit Mohanty, Girija Shankar Prasad Patro, and Kanhu Charan Patro. "To evaluate the impact of lignocaine and dexmedetomidine on hemodynamic reactions and airway reflexes during tracheal extubation in patients having laparoscopic operations." International Journal of Medical Reviews and Case Reports 6 (2022), 14-17. doi:10.5455/IJMRCR.172-1669715965


MLA (The Modern Language Association) Style

Swain, Avijeet, Yangyasmit Mohanty, Girija Shankar Prasad Patro, and Kanhu Charan Patro. "To evaluate the impact of lignocaine and dexmedetomidine on hemodynamic reactions and airway reflexes during tracheal extubation in patients having laparoscopic operations." International Journal of Medical Reviews and Case Reports 6.20 (2022), 14-17. Print. doi:10.5455/IJMRCR.172-1669715965


APA (American Psychological Association) Style

Swain, A., Mohanty, . Y., Patro, . G. S. P. & Patro, . K. C. (2022) To evaluate the impact of lignocaine and dexmedetomidine on hemodynamic reactions and airway reflexes during tracheal extubation in patients having laparoscopic operations. International Journal of Medical Reviews and Case Reports, 6 (20), 14-17. doi:10.5455/IJMRCR.172-1669715965


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