E-ISSN 2534-9821
 

Case Report
Online Published: 27 Jun 2020
 


Primary Central Nervous System Lymphoma (PCNSL) Type Diffuse Large B Cell in Immunocompetent Patient: A Case Report

Anak Agung Ayu Pramaswari, Anak Agung Ayu Putri Laksmidewi, I Made Oka Adnyana, I Putu Eka Widyadharma.


Abstract
Primary central nervous system lymphoma (PCNSL) is characterized as an extra-nodal non-Hodgkin lymphoma, which is a rare type of brain tumor. PCNSL often happens in an immunocompromised patient and rarely showed in an immunocompetent patient. This is a case of a 63-year-old man with a supratentorial tumor who first suspected as high-grade astrocytoma and underwent resection for his tumor, and the result showed PCNSL with diffuse large B Cell in histopathology. The patient was then admitted to neurology department for general weakness and mass in his forehead. CT scan and MRI brain examinations revealed a relapsed tumor in his left fronto-temporo-parietal lobe that was surrounded by edema and was enhancing after intravenous contrast administration. Histological and immunochemistry analysis of the resected specimen showed primary diffuse large B-cell lymphoma with CD20 positive. Radiation therapy was applied to the patient without chemotherapy, and at his last follow-up (after fifth radiation), the clinical appearance of the patient is better. The role of radiation probably should be reconsidered for PCNSL tumors.

Key words: Diffuse large B-cell Lymphoma, Immunocompetent, Primary Central Nervous System Lymphoma (PCNSL), Radiotherapy


 
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How to Cite this Article
Pubmed Style

Pramaswari AAA, Laksmidewi AAAP, Adnyana IMO, Widyadharma IPE. Primary Central Nervous System Lymphoma (PCNSL) Type Diffuse Large B Cell in Immunocompetent Patient: A Case Report. Int J Med Rev Case Rep. 2020; 4(11): 90-94. doi:10.5455/IJMRCR.Primary-Central-Nervous-System-Lymphoma


Web Style

Pramaswari AAA, Laksmidewi AAAP, Adnyana IMO, Widyadharma IPE. Primary Central Nervous System Lymphoma (PCNSL) Type Diffuse Large B Cell in Immunocompetent Patient: A Case Report. https://www.mdpub.net/?mno=90925 [Access: October 14, 2024]. doi:10.5455/IJMRCR.Primary-Central-Nervous-System-Lymphoma


AMA (American Medical Association) Style

Pramaswari AAA, Laksmidewi AAAP, Adnyana IMO, Widyadharma IPE. Primary Central Nervous System Lymphoma (PCNSL) Type Diffuse Large B Cell in Immunocompetent Patient: A Case Report. Int J Med Rev Case Rep. 2020; 4(11): 90-94. doi:10.5455/IJMRCR.Primary-Central-Nervous-System-Lymphoma



Vancouver/ICMJE Style

Pramaswari AAA, Laksmidewi AAAP, Adnyana IMO, Widyadharma IPE. Primary Central Nervous System Lymphoma (PCNSL) Type Diffuse Large B Cell in Immunocompetent Patient: A Case Report. Int J Med Rev Case Rep. (2020), [cited October 14, 2024]; 4(11): 90-94. doi:10.5455/IJMRCR.Primary-Central-Nervous-System-Lymphoma



Harvard Style

Pramaswari, A. A. A., Laksmidewi, . A. A. A. P., Adnyana, . I. M. O. & Widyadharma, . I. P. E. (2020) Primary Central Nervous System Lymphoma (PCNSL) Type Diffuse Large B Cell in Immunocompetent Patient: A Case Report. Int J Med Rev Case Rep, 4 (11), 90-94. doi:10.5455/IJMRCR.Primary-Central-Nervous-System-Lymphoma



Turabian Style

Pramaswari, Anak Agung Ayu, Anak Agung Ayu Putri Laksmidewi, I Made Oka Adnyana, and I Putu Eka Widyadharma. 2020. Primary Central Nervous System Lymphoma (PCNSL) Type Diffuse Large B Cell in Immunocompetent Patient: A Case Report. International Journal of Medical Reviews and Case Reports, 4 (11), 90-94. doi:10.5455/IJMRCR.Primary-Central-Nervous-System-Lymphoma



Chicago Style

Pramaswari, Anak Agung Ayu, Anak Agung Ayu Putri Laksmidewi, I Made Oka Adnyana, and I Putu Eka Widyadharma. "Primary Central Nervous System Lymphoma (PCNSL) Type Diffuse Large B Cell in Immunocompetent Patient: A Case Report." International Journal of Medical Reviews and Case Reports 4 (2020), 90-94. doi:10.5455/IJMRCR.Primary-Central-Nervous-System-Lymphoma



MLA (The Modern Language Association) Style

Pramaswari, Anak Agung Ayu, Anak Agung Ayu Putri Laksmidewi, I Made Oka Adnyana, and I Putu Eka Widyadharma. "Primary Central Nervous System Lymphoma (PCNSL) Type Diffuse Large B Cell in Immunocompetent Patient: A Case Report." International Journal of Medical Reviews and Case Reports 4.11 (2020), 90-94. Print. doi:10.5455/IJMRCR.Primary-Central-Nervous-System-Lymphoma



APA (American Psychological Association) Style

Pramaswari, A. A. A., Laksmidewi, . A. A. A. P., Adnyana, . I. M. O. & Widyadharma, . I. P. E. (2020) Primary Central Nervous System Lymphoma (PCNSL) Type Diffuse Large B Cell in Immunocompetent Patient: A Case Report. International Journal of Medical Reviews and Case Reports, 4 (11), 90-94. doi:10.5455/IJMRCR.Primary-Central-Nervous-System-Lymphoma