E-ISSN 2534-9821
 

Original Article 


Clinicopathological study of synovial lesions

Sahana V V, Suja Ajoykumar, Rajendra Prasad Prasad K N.

Abstract
Introduction:
Synovium is a specialized mesenchymal tissue that reacts to a wide variety of changes and noxious influences originating locally or elsewhere in the body. Histopathological examination of synovial biopsy plays a vital role in distinguishing between various possible etiologies such as infective, traumatic or crystal-induced arthropathy, and neoplastic lesions. Clinical and radiological findings are also essential in arriving at an accurate diagnosis of synovial lesions.
Aims and objectives: To study the spectrum of synovial lesions and correlate clinico-radiological findings of various lesions into degenerative, infective, inflammatory and neoplastic lesions.
Methods: All the synovial biopsy specimens received in the Pathology laboratory, KIMS Hospital and Research Centre were studied. A detailed histopathological study of the sections was done. Relevant clinical and radiological findings were analysed.
Results: In the present study, the common age groups affected were between the 2nd decade to the 3rd decade (31.1%) and above the 5th decade(31.1%). Females (56.6%) were more commonly affected. The knee joint (43.3%) showed a predilection for most of the synovial lesions. Among all the cases most common was tumour-like lesions (42.2%) followed by inflammatory lesions(19.9%), degenerative lesions (16.6%),infective lesions (9.9%), benign (9.9%) and malignant lesion (1.1%).
Conclusion: The majority of synovial lesions have identical clinical findings which can be classified into various subgroups by histopathological study. The study of synovial biopsy is a useful diagnostic tool in assessing various joint diseases.

Key words: Immunohistochemistry, Crystal Induced Arthropathy, Histopathology


 
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How to Cite this Article
Pubmed Style

V SV, Ajoykumar S, N RPPK. Clinicopathological study of synovial lesions. Int J Med Rev Case Rep. 2022; 6(1): 87-93. doi:10.5455/IJMRCR.CLINICOPATHOLOGICALSTUDYOFSYNOVIALLESIONS


Web Style

V SV, Ajoykumar S, N RPPK. Clinicopathological study of synovial lesions. https://www.mdpub.net/?mno=94400 [Access: September 12, 2022]. doi:10.5455/IJMRCR.CLINICOPATHOLOGICALSTUDYOFSYNOVIALLESIONS


AMA (American Medical Association) Style

V SV, Ajoykumar S, N RPPK. Clinicopathological study of synovial lesions. Int J Med Rev Case Rep. 2022; 6(1): 87-93. doi:10.5455/IJMRCR.CLINICOPATHOLOGICALSTUDYOFSYNOVIALLESIONS



Vancouver/ICMJE Style

V SV, Ajoykumar S, N RPPK. Clinicopathological study of synovial lesions. Int J Med Rev Case Rep. (2022), [cited September 12, 2022]; 6(1): 87-93. doi:10.5455/IJMRCR.CLINICOPATHOLOGICALSTUDYOFSYNOVIALLESIONS



Harvard Style

V, S. V., Ajoykumar, . S. & N, . R. P. P. K. (2022) Clinicopathological study of synovial lesions. Int J Med Rev Case Rep, 6 (1), 87-93. doi:10.5455/IJMRCR.CLINICOPATHOLOGICALSTUDYOFSYNOVIALLESIONS



Turabian Style

V, Sahana V, Suja Ajoykumar, and Rajendra Prasad Prasad K N. 2022. Clinicopathological study of synovial lesions. International Journal of Medical Reviews and Case Reports, 6 (1), 87-93. doi:10.5455/IJMRCR.CLINICOPATHOLOGICALSTUDYOFSYNOVIALLESIONS



Chicago Style

V, Sahana V, Suja Ajoykumar, and Rajendra Prasad Prasad K N. "Clinicopathological study of synovial lesions." International Journal of Medical Reviews and Case Reports 6 (2022), 87-93. doi:10.5455/IJMRCR.CLINICOPATHOLOGICALSTUDYOFSYNOVIALLESIONS



MLA (The Modern Language Association) Style

V, Sahana V, Suja Ajoykumar, and Rajendra Prasad Prasad K N. "Clinicopathological study of synovial lesions." International Journal of Medical Reviews and Case Reports 6.1 (2022), 87-93. Print. doi:10.5455/IJMRCR.CLINICOPATHOLOGICALSTUDYOFSYNOVIALLESIONS



APA (American Psychological Association) Style

V, S. V., Ajoykumar, . S. & N, . R. P. P. K. (2022) Clinicopathological study of synovial lesions. International Journal of Medical Reviews and Case Reports, 6 (1), 87-93. doi:10.5455/IJMRCR.CLINICOPATHOLOGICALSTUDYOFSYNOVIALLESIONS