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Case Report

Online Publishing Date:
28 / 02 / 2022

 


A Sporadic Case of Lofgren Syndrome in a 32 year old Nigerian man. A rare finding in Sub-Saharan Africa: A case report

John Omotola Ogunkoya, Akolade Idowu, Taamaka Davis Ngubor, ThankGod Aaron Uka, Onome Tobore Imishue.


Abstract
Introduction: Lofgren Syndrome (LS), a phenotype of Sarcoidosis is an acute inflammatory disease with pulmonary and extrapulmonary presentations. It is rarely seen in West Africans.
Case summary: The index patient presented with fever, pain and swelling of the wrist and ankle joints bilaterally, subcutaneous swellings (erythema nodosum) over the shin and extensor surfaces of the forearms and radiographic evidence of bilateral hilar adenopathy. Laboratory results showed elevated serum calcium, Angiotensin-converting enzyme (ACE), Aspartate transaminase (AST), Alanine transaminase (ALT), Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP).
Treatment: The patient was placed on a non-steroidal anti-inflammatory drug (oral diclofenac) and oral corticosteroid (methylprednisolone) with significant pain relief within the first 1week of commencement of medications. Oral diclofenac was discontinued after 1 week and oral methylprednisolone was tailed down after 3 weeks.
Conclusion: Though rare amongst Sub-Saharan Africans, documented cases of Lofgren syndrome are increasing in number. The clinician practising in sub-Saharan Africa should be open-minded and broaden his differential to include Lofgren syndrome especially typical features are present.

Key words: Erythema nodosum, Lofgren's syndrome, Lupus pernio, Sarcoidosis


 
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How to Cite this Article
Pubmed Style

Ogunkoya JO, Idowu A, Ngubor TD, Uka TA, Imishue OT. A Sporadic Case of Lofgren Syndrome in a 32 year old Nigerian man. A rare finding in Sub-Saharan Africa: A case report. Int J Med Rev Case Rep. 2022; 6(2): 1-5. doi:10.5455/IJMRCR.LofgrenSyndrome-in-32-year-old-Nigerian-man

Web Style

Ogunkoya JO, Idowu A, Ngubor TD, Uka TA, Imishue OT. A Sporadic Case of Lofgren Syndrome in a 32 year old Nigerian man. A rare finding in Sub-Saharan Africa: A case report. https://www.mdpub.net/?mno=94569 [Access: April 04, 2024]. doi:10.5455/IJMRCR.LofgrenSyndrome-in-32-year-old-Nigerian-man

AMA (American Medical Association) Style

Ogunkoya JO, Idowu A, Ngubor TD, Uka TA, Imishue OT. A Sporadic Case of Lofgren Syndrome in a 32 year old Nigerian man. A rare finding in Sub-Saharan Africa: A case report. Int J Med Rev Case Rep. 2022; 6(2): 1-5. doi:10.5455/IJMRCR.LofgrenSyndrome-in-32-year-old-Nigerian-man


Vancouver/ICMJE Style

Ogunkoya JO, Idowu A, Ngubor TD, Uka TA, Imishue OT. A Sporadic Case of Lofgren Syndrome in a 32 year old Nigerian man. A rare finding in Sub-Saharan Africa: A case report. Int J Med Rev Case Rep. (2022), [cited April 04, 2024]; 6(2): 1-5. doi:10.5455/IJMRCR.LofgrenSyndrome-in-32-year-old-Nigerian-man


Harvard Style

Ogunkoya, J. O., Idowu, . A., Ngubor, . T. D., Uka, . T. A. & Imishue, . O. T. (2022) A Sporadic Case of Lofgren Syndrome in a 32 year old Nigerian man. A rare finding in Sub-Saharan Africa: A case report. Int J Med Rev Case Rep, 6 (2), 1-5. doi:10.5455/IJMRCR.LofgrenSyndrome-in-32-year-old-Nigerian-man


Turabian Style

Ogunkoya, John Omotola, Akolade Idowu, Taamaka Davis Ngubor, ThankGod Aaron Uka, and Onome Tobore Imishue. 2022. A Sporadic Case of Lofgren Syndrome in a 32 year old Nigerian man. A rare finding in Sub-Saharan Africa: A case report. International Journal of Medical Reviews and Case Reports, 6 (2), 1-5. doi:10.5455/IJMRCR.LofgrenSyndrome-in-32-year-old-Nigerian-man


Chicago Style

Ogunkoya, John Omotola, Akolade Idowu, Taamaka Davis Ngubor, ThankGod Aaron Uka, and Onome Tobore Imishue. "A Sporadic Case of Lofgren Syndrome in a 32 year old Nigerian man. A rare finding in Sub-Saharan Africa: A case report." International Journal of Medical Reviews and Case Reports 6 (2022), 1-5. doi:10.5455/IJMRCR.LofgrenSyndrome-in-32-year-old-Nigerian-man


MLA (The Modern Language Association) Style

Ogunkoya, John Omotola, Akolade Idowu, Taamaka Davis Ngubor, ThankGod Aaron Uka, and Onome Tobore Imishue. "A Sporadic Case of Lofgren Syndrome in a 32 year old Nigerian man. A rare finding in Sub-Saharan Africa: A case report." International Journal of Medical Reviews and Case Reports 6.2 (2022), 1-5. Print. doi:10.5455/IJMRCR.LofgrenSyndrome-in-32-year-old-Nigerian-man


APA (American Psychological Association) Style

Ogunkoya, J. O., Idowu, . A., Ngubor, . T. D., Uka, . T. A. & Imishue, . O. T. (2022) A Sporadic Case of Lofgren Syndrome in a 32 year old Nigerian man. A rare finding in Sub-Saharan Africa: A case report. International Journal of Medical Reviews and Case Reports, 6 (2), 1-5. doi:10.5455/IJMRCR.LofgrenSyndrome-in-32-year-old-Nigerian-man


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