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Online Publishing Date:
27 / 12 / 2022

 


Dengue Infection - Seroprevalence and Seasonal Variation among patients attending a Tertiary Care Hospital at Visakhapatnam, Andhra Pradesh, India

Vijaya Bharathi Dondapati, Pradeep Marey, Narasinga Rao Bandaru, Bala Murali Krishna Perala, Manasa Sireesha Devara, Archana Voleti.


Abstract
Introduction: Dengue infections have become a considerable threat to public health systems in developing countries. This study determines seroprevalence of dengue virus, seropositivity of Dengue NS1 antigen, IgM and IgG antibodies, Seasonal variation of dengue infection, and demographic profile of dengue-positive patients.
Methods:
A retrospective study was conducted at the Microbiology Department of Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, India, from January 2018 to December 2019. A total of 5554 samples were collected from patients who were suspected of suffering from Dengue fever in the Medicine and Paediatrics wards.
The patients were checked using Dengue Duo rapid test method from a commercial supply for combined Dengue NS1 antigen, IgM, and IgG antibody detection.
Results:
A total of 5554 serum samples were analyzed, among which 1045 were Dengue positive. The seroprevalence of dengue was 21.13% (95% confidence intervals (CI) 19.8– 22.6%) in 2018 and 15.40% (95% CI 13.9– 16.9%) in 2019. NS1 was positive in 835 (79.9%), IgM was positive in 26 (2.48%), IgG was positive in 116 (11.10%), and 68 were positive with both antigens and both antibodies. An outbreak occurred from July to October, indicating increased vector transmission in the monsoon and post-monsoon periods.
Conclusion: The present study confirms that Dengue is mainly a disease of the rainy season, and effective implementation of vector control measures through efforts toward vector breeding source reduction and using personal prophylactic measures against mosquito bites will help in reducing the dengue prevalence in the community.

Key words: Dengue, Seroprevalence, Aedes aegypti, NS1antigen, IgM and IgG antibodies


 
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How to Cite this Article
Pubmed Style

Dondapati VB, Marey P, Bandaru NR, Perala BMK, Devara MS, Voleti A. Dengue Infection - Seroprevalence and Seasonal Variation among patients attending a Tertiary Care Hospital at Visakhapatnam, Andhra Pradesh, India. Int J Med Rev Case Rep. 2022; 6(18): 32-36. doi:10.5455/IJMRCR.172-1661159474

Web Style

Dondapati VB, Marey P, Bandaru NR, Perala BMK, Devara MS, Voleti A. Dengue Infection - Seroprevalence and Seasonal Variation among patients attending a Tertiary Care Hospital at Visakhapatnam, Andhra Pradesh, India. https://www.mdpub.net/?mno=108038 [Access: April 04, 2024]. doi:10.5455/IJMRCR.172-1661159474

AMA (American Medical Association) Style

Dondapati VB, Marey P, Bandaru NR, Perala BMK, Devara MS, Voleti A. Dengue Infection - Seroprevalence and Seasonal Variation among patients attending a Tertiary Care Hospital at Visakhapatnam, Andhra Pradesh, India. Int J Med Rev Case Rep. 2022; 6(18): 32-36. doi:10.5455/IJMRCR.172-1661159474


Vancouver/ICMJE Style

Dondapati VB, Marey P, Bandaru NR, Perala BMK, Devara MS, Voleti A. Dengue Infection - Seroprevalence and Seasonal Variation among patients attending a Tertiary Care Hospital at Visakhapatnam, Andhra Pradesh, India. Int J Med Rev Case Rep. (2022), [cited April 04, 2024]; 6(18): 32-36. doi:10.5455/IJMRCR.172-1661159474


Harvard Style

Dondapati, V. B., Marey, . P., Bandaru, . N. R., Perala, . B. M. K., Devara, . M. S. & Voleti, . A. (2022) Dengue Infection - Seroprevalence and Seasonal Variation among patients attending a Tertiary Care Hospital at Visakhapatnam, Andhra Pradesh, India. Int J Med Rev Case Rep, 6 (18), 32-36. doi:10.5455/IJMRCR.172-1661159474


Turabian Style

Dondapati, Vijaya Bharathi, Pradeep Marey, Narasinga Rao Bandaru, Bala Murali Krishna Perala, Manasa Sireesha Devara, and Archana Voleti. 2022. Dengue Infection - Seroprevalence and Seasonal Variation among patients attending a Tertiary Care Hospital at Visakhapatnam, Andhra Pradesh, India. International Journal of Medical Reviews and Case Reports, 6 (18), 32-36. doi:10.5455/IJMRCR.172-1661159474


Chicago Style

Dondapati, Vijaya Bharathi, Pradeep Marey, Narasinga Rao Bandaru, Bala Murali Krishna Perala, Manasa Sireesha Devara, and Archana Voleti. "Dengue Infection - Seroprevalence and Seasonal Variation among patients attending a Tertiary Care Hospital at Visakhapatnam, Andhra Pradesh, India." International Journal of Medical Reviews and Case Reports 6 (2022), 32-36. doi:10.5455/IJMRCR.172-1661159474


MLA (The Modern Language Association) Style

Dondapati, Vijaya Bharathi, Pradeep Marey, Narasinga Rao Bandaru, Bala Murali Krishna Perala, Manasa Sireesha Devara, and Archana Voleti. "Dengue Infection - Seroprevalence and Seasonal Variation among patients attending a Tertiary Care Hospital at Visakhapatnam, Andhra Pradesh, India." International Journal of Medical Reviews and Case Reports 6.18 (2022), 32-36. Print. doi:10.5455/IJMRCR.172-1661159474


APA (American Psychological Association) Style

Dondapati, V. B., Marey, . P., Bandaru, . N. R., Perala, . B. M. K., Devara, . M. S. & Voleti, . A. (2022) Dengue Infection - Seroprevalence and Seasonal Variation among patients attending a Tertiary Care Hospital at Visakhapatnam, Andhra Pradesh, India. International Journal of Medical Reviews and Case Reports, 6 (18), 32-36. doi:10.5455/IJMRCR.172-1661159474


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