E-ISSN 2534-9821
 

Letter to the Editor 


Potential clinical relevance of the common pathophysiological pathway in Kounis syndrome and non allergic acute coronary syndrome

Domina Petric.

Abstract
Kounis syndrome is an acute coronary syndrome associated with mast cell and platelet activation in the setting of allergic or anaphylactic reactions. The mediators released from the same inflammatory cells are also present in acute coronary events of a non-allergic aetiology. There is sufficient evidence about the common pathophysiological pathway between allergic and non-allergic acute coronary syndrome, with mast cells and pro-inflammatory molecules such as histamine, tryptase, chymase, thromboxane, leukotrienes, and IL-6, playing a crucial role. On the other hand, there is no sufficient evidence to support intravenous corticosteroids and/or antihistamines in non-allergic acute coronary syndrome, but further clinical research might be relevant.

Key words: Kounis syndrome, corticosteroids, pathophysiology


 
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How to Cite this Article
Pubmed Style

Domina Petric. Potential clinical relevance of the common pathophysiological pathway in Kounis syndrome and non allergic acute coronary syndrome. Int J Med Rev Case Rep. 2022; 6(14): 14-15. doi:10.5455/IJMRCR.172-1644937731


Web Style

Domina Petric. Potential clinical relevance of the common pathophysiological pathway in Kounis syndrome and non allergic acute coronary syndrome. https://www.mdpub.net/?mno=58788 [Access: November 19, 2022]. doi:10.5455/IJMRCR.172-1644937731


AMA (American Medical Association) Style

Domina Petric. Potential clinical relevance of the common pathophysiological pathway in Kounis syndrome and non allergic acute coronary syndrome. Int J Med Rev Case Rep. 2022; 6(14): 14-15. doi:10.5455/IJMRCR.172-1644937731



Vancouver/ICMJE Style

Domina Petric. Potential clinical relevance of the common pathophysiological pathway in Kounis syndrome and non allergic acute coronary syndrome. Int J Med Rev Case Rep. (2022), [cited November 19, 2022]; 6(14): 14-15. doi:10.5455/IJMRCR.172-1644937731



Harvard Style

Domina Petric (2022) Potential clinical relevance of the common pathophysiological pathway in Kounis syndrome and non allergic acute coronary syndrome. Int J Med Rev Case Rep, 6 (14), 14-15. doi:10.5455/IJMRCR.172-1644937731



Turabian Style

Domina Petric. 2022. Potential clinical relevance of the common pathophysiological pathway in Kounis syndrome and non allergic acute coronary syndrome. International Journal of Medical Reviews and Case Reports, 6 (14), 14-15. doi:10.5455/IJMRCR.172-1644937731



Chicago Style

Domina Petric. "Potential clinical relevance of the common pathophysiological pathway in Kounis syndrome and non allergic acute coronary syndrome." International Journal of Medical Reviews and Case Reports 6 (2022), 14-15. doi:10.5455/IJMRCR.172-1644937731



MLA (The Modern Language Association) Style

Domina Petric. "Potential clinical relevance of the common pathophysiological pathway in Kounis syndrome and non allergic acute coronary syndrome." International Journal of Medical Reviews and Case Reports 6.14 (2022), 14-15. Print. doi:10.5455/IJMRCR.172-1644937731



APA (American Psychological Association) Style

Domina Petric (2022) Potential clinical relevance of the common pathophysiological pathway in Kounis syndrome and non allergic acute coronary syndrome. International Journal of Medical Reviews and Case Reports, 6 (14), 14-15. doi:10.5455/IJMRCR.172-1644937731