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Case Report
Online Published: 13 Jun 2021
 


Aggressive systemic mastocytosis: a silent enemy

Joana Alves Vaz, Maria Alice Sousa, Celina Afonso, Rita Sampaio.


Abstract
Mastocytosis results from the accumulation, proliferation and activation of mast cells with the involvement of several organs. The skin, bone marrow, gastrointestinal tract, liver, spleen and lymph nodes are the most frequent locations. Symptoms result from the accumulation of mast cells and the release of mediators from their activation. The incidence of this pathology is rare and, depending on the presentation, the diagnosis can be difficult. Systemic presentation is more frequent in adults, in contrast to the pediatric population, where skin disease prevails and with a good prognosis.
The authors describe the case of a man diagnosed with chronic anaemia and being followed up in a Hematology consultation who presents with anorexia, asthenia and weight loss. After inpatient assessment, the diagnosis of aggressive systemic mastocytosis was established.

Key words: Aggressive systemic mastocytosis, chronic anaemia


 
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How to Cite this Article
Pubmed Style

Vaz JA, Sousa MA, Afonso C, Sampaio R. Aggressive systemic mastocytosis: a silent enemy. Int J Med Rev Case Rep. 2021; 5(5): 106-108. doi:10.5455/IJMRCR.Aggressive-systemic-mastocytosis

Web Style

Vaz JA, Sousa MA, Afonso C, Sampaio R. Aggressive systemic mastocytosis: a silent enemy. https://www.mdpub.net/?mno=62461 [Access: April 02, 2025]. doi:10.5455/IJMRCR.Aggressive-systemic-mastocytosis

AMA (American Medical Association) Style

Vaz JA, Sousa MA, Afonso C, Sampaio R. Aggressive systemic mastocytosis: a silent enemy. Int J Med Rev Case Rep. 2021; 5(5): 106-108. doi:10.5455/IJMRCR.Aggressive-systemic-mastocytosis


Vancouver/ICMJE Style

Vaz JA, Sousa MA, Afonso C, Sampaio R. Aggressive systemic mastocytosis: a silent enemy. Int J Med Rev Case Rep. (2021), [cited April 02, 2025]; 5(5): 106-108. doi:10.5455/IJMRCR.Aggressive-systemic-mastocytosis


Harvard Style

Vaz, J. A., Sousa, . M. A., Afonso, . C. & Sampaio, . R. (2021) Aggressive systemic mastocytosis: a silent enemy. Int J Med Rev Case Rep, 5 (5), 106-108. doi:10.5455/IJMRCR.Aggressive-systemic-mastocytosis


Turabian Style

Vaz, Joana Alves, Maria Alice Sousa, Celina Afonso, and Rita Sampaio. 2021. Aggressive systemic mastocytosis: a silent enemy. International Journal of Medical Reviews and Case Reports, 5 (5), 106-108. doi:10.5455/IJMRCR.Aggressive-systemic-mastocytosis


Chicago Style

Vaz, Joana Alves, Maria Alice Sousa, Celina Afonso, and Rita Sampaio. "Aggressive systemic mastocytosis: a silent enemy." International Journal of Medical Reviews and Case Reports 5 (2021), 106-108. doi:10.5455/IJMRCR.Aggressive-systemic-mastocytosis


MLA (The Modern Language Association) Style

Vaz, Joana Alves, Maria Alice Sousa, Celina Afonso, and Rita Sampaio. "Aggressive systemic mastocytosis: a silent enemy." International Journal of Medical Reviews and Case Reports 5.5 (2021), 106-108. Print. doi:10.5455/IJMRCR.Aggressive-systemic-mastocytosis


APA (American Psychological Association) Style

Vaz, J. A., Sousa, . M. A., Afonso, . C. & Sampaio, . R. (2021) Aggressive systemic mastocytosis: a silent enemy. International Journal of Medical Reviews and Case Reports, 5 (5), 106-108. doi:10.5455/IJMRCR.Aggressive-systemic-mastocytosis


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