Abstract
Objectives: The aim of this experimental study is to contribute to the elucidation of the etiopathogenesis of recurrence and to investigate the effect of thermal energy on neovascularization in Sapheno-Femoral Junction (SFJ) divisions. Methods: Seven adult wistar rats have been used for each group. The left legs of the same rats without any attemp were accepted as the control group. The other groups were named surgical and Endovascular laser ablasyon (EVLA) group respectively, after right femoral venous binding, with scissor divide and directly with cotter divide. After routine light microscopic tissue processing; tissue samples were stained by Hemotoxylin-Eosin and VEGF. In light microscopic sections, capillaries were counted with 10 different field x20 lens magnification, and the average was taken and H-Scores were determined. For the statistical analysis, the Spousal T Test was applied and the groups were compared according to the result. Kolmogorov-Simirnov Test was applied to individual distributions of each group. Results: In statistical analysis; the Kolmogorov-Simirnov test was normally distributed separately (p>0,05). In VEGF immunostaining; while there was statistically significant difference between Control and Surgery group (p: 0,001), between Surgery and EVLA group (p: 0,039) and there was no statistically significant difference between Control and EVLA group (P: 0,199). Conclusions: In our study, it was observed that the use of thermal ablation in EVLA application of varicose vein surgery in SFJ reduced neovascularization emerging in varicose vein recurrence. EVLA may be an easily applicable, minimally invasive and alternative way of preventing varicose venous recurrences.

Key words: Chronıc venous insuffıcıency, Neovascularızatıon, recurrence of varicose vein, EVLA