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Original Article

Online Publishing Date:
10 / 05 / 2022

 


Role of MRCP as pre-operative investigation in cholelithiasis patients and its correlation with liver function tests and USG abdomen for choledocolithiasis -A longitudinal study

Gurpreet Mann, Deepak Kumar Gupta, Dushyant Kumar Garg, Nikhil Mahajan.


Abstract
Introduction:
Cholelithiasis is a common surgical diagnosis and Laparoscopic cholecystectomy is a common surgical procedure. One of the postoperative complications of Laparoscopic cholecystectomy is retained bile duct stone due to failure of diagnosing these preoperatively. This leads to increased morbidity and mortality in post-cholecystectomy patients. USG abdomen and liver function tests are routinely done preoperatively in cholelithiasis patients. These have poor sensitivity and specificity for diagnosing CBD stones. MRCP is a highly sensitive and specific investigation for CBD stone detection.
Aim:
To evaluate the role of routine MRCP in all patients of cholelithiasis and its correlation with liver function test (S. Bilirubin, SGOT, SGPT and S. Alkaline phosphatase) and ultrasound abdomen for diagnosing CBD stones.
Material and Methods
The present study was a longitudinal study done on 100 patients diagnosed to have cholelithiasis on an ultrasound abdomen with no CBD stone. All the patients were investigated with liver function tests and MRCP pre-operatively for detection of missed CBD stones. Data were analyzed with SPSS software and a chi-square test was used and a p-value <0.05 was considered a level of significance.
Results:
The mean age of patients in this study was 52.47 years with a standard deviation of ± 41. 59 patients were female and 41 were male. Among all the 100 patients, who reported normal CBD on ultrasound abdomen, in 20 patients CBD stone was detected on MRCP. Raised liver enzymes were also related to CBD stone. Raised S. bilirubin has a PPV-66.7%, NPV – 82.97%, sensitivity-20% and specificity of 97.5%. Raised SGOT/SGPT had a PPV of 55%, NPV -88.75%, sensitivity- 55% and specificity of 88.75%. Raised S. Alkaline phosphatase has a PPV- 76%, NOV – 89.15%, sensitivity-67.85% and specificity of 92.5%.
Conclusion:
Routine MRCP should be done in all patients of cholelithiasis preoperatively to avoid the complication of retained common bile duct stones.

Key words: CBD stone, Raised Liver Function Tests, postoperative cholecystectomy patients


 
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How to Cite this Article
Pubmed Style

Mann G, Gupta DK, Garg DK, Mahajan N. Role of MRCP as pre-operative investigation in cholelithiasis patients and its correlation with liver function tests and USG abdomen for choledocolithiasis -A longitudinal study. Int J Med Rev Case Rep. 2022; 6(7): 84-88. doi:10.5455/IJMRCR.172-1649675876

Web Style

Mann G, Gupta DK, Garg DK, Mahajan N. Role of MRCP as pre-operative investigation in cholelithiasis patients and its correlation with liver function tests and USG abdomen for choledocolithiasis -A longitudinal study. https://www.mdpub.net/?mno=9157 [Access: April 04, 2024]. doi:10.5455/IJMRCR.172-1649675876

AMA (American Medical Association) Style

Mann G, Gupta DK, Garg DK, Mahajan N. Role of MRCP as pre-operative investigation in cholelithiasis patients and its correlation with liver function tests and USG abdomen for choledocolithiasis -A longitudinal study. Int J Med Rev Case Rep. 2022; 6(7): 84-88. doi:10.5455/IJMRCR.172-1649675876


Vancouver/ICMJE Style

Mann G, Gupta DK, Garg DK, Mahajan N. Role of MRCP as pre-operative investigation in cholelithiasis patients and its correlation with liver function tests and USG abdomen for choledocolithiasis -A longitudinal study. Int J Med Rev Case Rep. (2022), [cited April 04, 2024]; 6(7): 84-88. doi:10.5455/IJMRCR.172-1649675876


Harvard Style

Mann, G., Gupta, . D. K., Garg, . D. K. & Mahajan, . N. (2022) Role of MRCP as pre-operative investigation in cholelithiasis patients and its correlation with liver function tests and USG abdomen for choledocolithiasis -A longitudinal study. Int J Med Rev Case Rep, 6 (7), 84-88. doi:10.5455/IJMRCR.172-1649675876


Turabian Style

Mann, Gurpreet, Deepak Kumar Gupta, Dushyant Kumar Garg, and Nikhil Mahajan. 2022. Role of MRCP as pre-operative investigation in cholelithiasis patients and its correlation with liver function tests and USG abdomen for choledocolithiasis -A longitudinal study. International Journal of Medical Reviews and Case Reports, 6 (7), 84-88. doi:10.5455/IJMRCR.172-1649675876


Chicago Style

Mann, Gurpreet, Deepak Kumar Gupta, Dushyant Kumar Garg, and Nikhil Mahajan. "Role of MRCP as pre-operative investigation in cholelithiasis patients and its correlation with liver function tests and USG abdomen for choledocolithiasis -A longitudinal study." International Journal of Medical Reviews and Case Reports 6 (2022), 84-88. doi:10.5455/IJMRCR.172-1649675876


MLA (The Modern Language Association) Style

Mann, Gurpreet, Deepak Kumar Gupta, Dushyant Kumar Garg, and Nikhil Mahajan. "Role of MRCP as pre-operative investigation in cholelithiasis patients and its correlation with liver function tests and USG abdomen for choledocolithiasis -A longitudinal study." International Journal of Medical Reviews and Case Reports 6.7 (2022), 84-88. Print. doi:10.5455/IJMRCR.172-1649675876


APA (American Psychological Association) Style

Mann, G., Gupta, . D. K., Garg, . D. K. & Mahajan, . N. (2022) Role of MRCP as pre-operative investigation in cholelithiasis patients and its correlation with liver function tests and USG abdomen for choledocolithiasis -A longitudinal study. International Journal of Medical Reviews and Case Reports, 6 (7), 84-88. doi:10.5455/IJMRCR.172-1649675876


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