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Case Report
Online Published: 27 Feb 2021
 


Cholestatic hepatitis as a presentation of Epstein-Barr virus infection

Mayara Nogueira, Joana Gaspar, Susana Gomes.


Cited By: 1

Abstract
Epstein-Barr virus (EBV) infection in children and adolescents clinically presents as infectious mononucleosis and usually leads to self limited elevation of liver enzymes but cholestatic hepatitis with jaundice is rare. We present a 16-year-old female with fever, fatigue, vomiting, choluria and jaundice. Physical examination showed a painful abdomen and the remaining examination was unremarkable. Laboratory tests results revealed leucocytosis and activated lymphocytes, normal haemoglobin level, the elevation of transaminases more than 7 times the upper limit, cholestasis and hypoalbuminemia. The abdominal ultrasound showed mild hepatosplenomegaly. Viral serologies revealed positive EBV viral capsid antibody IgM and negative IgG and were negative for other viral agents. Later she developed haemolytic anaemia. She received support treatment and fully recovered. We emphasize that EBV infection should be considered in patients with cholestatic hepatitis with jaundice.

Key words: Epstein-Barr virus, cholestasis, hepatitis, hyperbilirubinemia, jaundice


 
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How to Cite this Article
Pubmed Style

Nogueira M, Gaspar J, Gomes S. Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. Int J Med Rev Case Rep. 2021; 5(5): 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058

Web Style

Nogueira M, Gaspar J, Gomes S. Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. https://www.mdpub.net/?mno=53293 [Access: April 02, 2025]. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058

AMA (American Medical Association) Style

Nogueira M, Gaspar J, Gomes S. Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. Int J Med Rev Case Rep. 2021; 5(5): 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058


Vancouver/ICMJE Style

Nogueira M, Gaspar J, Gomes S. Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. Int J Med Rev Case Rep. (2021), [cited April 02, 2025]; 5(5): 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058


Harvard Style

Nogueira, M., Gaspar, . J. & Gomes, . S. (2021) Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. Int J Med Rev Case Rep, 5 (5), 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058


Turabian Style

Nogueira, Mayara, Joana Gaspar, and Susana Gomes. 2021. Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. International Journal of Medical Reviews and Case Reports, 5 (5), 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058


Chicago Style

Nogueira, Mayara, Joana Gaspar, and Susana Gomes. "Cholestatic hepatitis as a presentation of Epstein-Barr virus infection." International Journal of Medical Reviews and Case Reports 5 (2021), 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058


MLA (The Modern Language Association) Style

Nogueira, Mayara, Joana Gaspar, and Susana Gomes. "Cholestatic hepatitis as a presentation of Epstein-Barr virus infection." International Journal of Medical Reviews and Case Reports 5.5 (2021), 39-41. Print. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058


APA (American Psychological Association) Style

Nogueira, M., Gaspar, . J. & Gomes, . S. (2021) Cholestatic hepatitis as a presentation of Epstein-Barr virus infection. International Journal of Medical Reviews and Case Reports, 5 (5), 39-41. doi:10.5455/IJMRCR.Epstein-Barr-virus-infection-058


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